SS Constitution was featured in several episodes of the situation comedyI Love Lucy starring Lucille Ball and Desi Arnaz, starting with episode 140, "Bon Voyage," aired December 1, 1955. Lucy Ricardo missed the ship and had to be ferried by air by a then-novel helicopter.
American movie actress Grace Kelly sailed aboard SS Constitution from New York to Monaco for her wedding to Prince Rainier in 1956.
SS Constitution was featured in the 1957 film, An Affair to Remember starring Cary Grant and Deborah Kerr. She was also featured in the beginning and end of an episode of the Naked City TV series titled "No Naked Ladies in Front of Giovanni's House!" aired April 17, 1963. The ship also featured prominently in the Magnum, P.I. television series episode titled "All Thieves on Deck" aired January 30, 1986.