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Sulfur oxide refers to many types of sulfur and oxygen containing compounds such as SO, SO2, SO3, S7O2, S6O2, S2O2, etc.
Sulfur oxide (SOx) refers to one or more of the following:
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Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene.
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development.
In melanocytic cells there is evidence that SOX10 gene expression may be regulated by MITF.
Mutations in this gene are associated with Waardenburg-Shah, Waardenburg-Hirschsprung disease, and with uveal melanoma .
The interaction between SOX10 and PAX3 is studied best in human patients with Waardenburg syndrome, an autosomal dominant disorder which is divided into four different types based upon mutations in additional genes. SOX10 and PAX3 interactions are thought to be regulators of other genes involved in the symptoms of Waardenburg syndrome, particularly MITF which influences the development of melanocytes as well as neural crest formation. MITF expression can be transactivated by both SOX10 and PAX3 to have an additive effect. The two genes have binding sites near one another on the upstream enhancer of the c-RET gene. SOX10 is also thought to target dopachrome tautomerase through a synergistic interaction with MITF which then results in other melanocyte alteration.
Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene.
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
Sox4 is expressed in lymphocytes (B and T) and is required for B lymphocyte development.
SOX4 has been shown to interact with SDCBP.
He needs me
He doesn't know it, but he needs me
And so no matter where he goes
Though he doesn't care
He knows that I'm here
He needs me
I ought to leave him, but he needs me
I know that I'm not very bright
Just to tag along
Oh, but right or wrong
I'm his and I'm here
And I'm gonna be his friend or his lover
'Cause my one ambition is
To wake him and make him discover
That he needs me
I've got to follow where he leads me
Or else he'll never know that I need him