SNX4

Sorting nexin-4 is a protein that in humans is encoded by the SNX4 gene.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members.

Interactions

SNX4 has been shown to interact with BIN1.

References

Further reading

SNX2

Sorting nexin-2 is a protein that in humans is encoded by the SNX2 gene.

Function

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with formin-binding protein 17, but its function is unknown. This protein may form oligomeric complexes with family members.

Interactions

SNX2 has been shown to interact with FNBP1.

References

Further reading

SNAG1

Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.

References

Further reading