SKF

SKF, Svenska Kullagerfabriken AB (Swedish: Swedish ball bearing factory AB), later AB SKF, is a leading bearing and seals manufacturing company founded in Gothenburg, Sweden in 1907. The company manufactures and supplies bearings, seals, lubrication and lubrication systems, maintenance products, mechatronics products, power transmission products, condition monitoring systems and related services globally.

Today, SKF is the largest bearing manufacturer in the world and employs approximately 48,600 people in 140 production and manufacturing sites, which in addition to 15,000 worldwide distribution locations encompasses 130 countries worldwide. With an annual Turnover of SEK 70.975 Billion, and total assets of SEK 81.639 Billion in FY2014, SKF has been listed as one of the largest companies in Sweden and among largest public companies in the world according to Forbes Global 2000 ranking.

History

Alazocine

Alazocine ((-)-SKF-10,047), or (-)-N-allylnormetazocine ((-)-ANMC), was the first drug discovered to act as a σ₁ receptor agonist (K_i = 24 nM). It has no significant affinity for the σ₂ receptor. Alazocine also acts as a κ-opioid receptor agonist (K_i = 0.4 nM), and to a much lesser extent, as an NMDA receptor antagonist (K_i = 587 nM).

See also

References

SKF-38,393

SKF-38,393 is a synthetic compound of the benzazepine chemical class which acts as a selective D₁/D₅ receptor partial agonist. It has stimulant and anorectic effects.

References