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Soc-2 suppressor of clear homolog (C. elegans)
Identifiers
Symbols SHOC2; SIAA0862; SOC2; SUR8
External IDs OMIM: 602775 MGI: 1927197 HomoloGene: 7219 GeneCards: SHOC2 Gene
RNA expression pattern
PBB GE SHOC2 202777 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8036 56392
Ensembl ENSG00000108061 ENSMUSG00000024976
UniProt Q9UQ13 O88520
RefSeq (mRNA) NM_007373.3 NM_001168505.1
RefSeq (protein) NP_031399.2 NP_001161977.1
Location (UCSC) Chr 10:
112.68 – 112.77 Mb		 Chr 19:
54.02 – 54.11 Mb
PubMed search [1] [2]
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Leucine-rich repeat protein SHOC-2 is a protein that in humans is encoded by the SHOC2 gene.[1][2][3][4]


Interactions [link]

SHOC2 has been shown to interact with C-Raf[3] and HRAS.[3]

References [link]

  1. ^ Selfors LM, Schutzman JL, Borland CZ, Stern MJ (Jul 1998). "soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling". Proc Natl Acad Sci U S A 95 (12): 6903–8. DOI:10.1073/pnas.95.12.6903. PMC 22679. PMID 9618511. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=22679. 
  2. ^ Sieburth DS, Sun Q, Han M (Aug 1998). "SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans". Cell 94 (1): 119–30. DOI:10.1016/S0092-8674(00)81227-1. PMID 9674433. 
  3. ^ a b c Li W, Han M, Guan KL (May 2000). "The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf". Genes Dev 14 (8): 895–900. PMC 316541. PMID 10783161. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=316541. 
  4. ^ "Entrez Gene: SHOC2 soc-2 suppressor of clear homolog (C. elegans)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8036. 

Further reading [link]



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