SDC2

Syndecan-2 is a protein that in humans is encoded by the SDC2 gene.

Function

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

Interactions

SDC2 has been shown to interact with:

  • CASK,
  • Laminin, alpha 3, and
  • EZR
  • References

    Further reading


    Podcasts:

    PLAYLIST TIME:

    My Story

    by: Sticky Icky

    Verse one
    I haven't been in this ghetto life for long
    But in da time dat I've, I became strong
    I've been in fights, ruff nights
    All da things dat aint right
    Seen niggaz go down da hard way
    Been snitching, stupid niggaz dunno wat ta say
    U dunno ma life
    But u know, aint I got a wife
    All da stress dat passes ma way
    Gotta cum through every day
    I luvd ma mum, luvd ma pap
    Bee wit m when times were tough
    This all about ma life
    But also thnx 4 time witout a knife
    Ma niggas threatening wit a gun
    Started to blunder
    Pow lifes gone!
    Everyone starts to moan
    Stop da jealousy n' hate
    Stop fuckin' wit ya fate!
    Chorus
    This is ma life
    Every day its all about ma life
    Wat I gotta go through in ma life
    Some y'all been talkin' hating ma life
    But its ma life, but its ma life.
    Verse two
    Ma close friend lost his queen
    Shit it's a scene not 2b seen
    Talk about losing peace n' tranquility
    Stop at a mood of humidity
    Been tryna get into da musik industry
    What my future holds is juz a mystery
    But da question still remains
    Could I fulfill da dynasty
    It was hard getting here
    Da visa repeater
    N' all da forms we hadta clear
    Think we going there to sip beer
    Of cos afta we say, we here
    Please I got nu'in to fear
    Ill be raising da atmosphere
    Sit on da plane, whisper in her ear
    Mammy I wanna fuck ya in da rear
    All year!
    They know ama bad ass
    Don't put me in first class
    Ill start a real bash
    Dats wat they thought I was
    Dats why da ticket cost
    Cos I got black completion
    Think ama get an erection
    Fuck em stewardesses
    Juz by lifting em dresses
    Shit!
    Chorus
    This is ma life
    Every day its all about ma life
    Wat I gotta go through in ma life
    Some y'all been talkin' hating ma life
    But its ma life, but its ma life.
    Verse three
    Now I hit da stash
    These snitches n me clash
    They be thinkin' am trash
    Its cool, bring ya face, ama smash
    They know ma musik burns rubber
    Am da next idol like Ruben Studdard
    Aint gonna stutter stutter
    Gon get hotter hotta
    Ma lifes been well
    Roaming around in this realm
    Ma musik aint stale
    It goes through ya heart
    Sharp like a nail
    Bitch move! Slow like a snail
    Ama be tearing through yas
    U wanna produce ma musik, too cool
    This shits for no fool
    Try master ma musik, ma shit
    U aint got da tools.
    Chorus
    This is ma life
    Every day its all about ma life
    Wat I gotta go through in ma life
    Some y'all been talkin' hating ma life




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