| Sodium channel, voltage-gated, type IV, beta subunit | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | SCN4B; Navbeta4 | ||||||||||||
| External IDs | OMIM: 608256 MGI: 2687406 HomoloGene: 18384 ChEMBL: 4689 GeneCards: SCN4B Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 6330 | 399548 | |||||||||||
| Ensembl | ENSG00000177098 | ENSMUSG00000046480 | |||||||||||
| UniProt | Q8IWT1 | Q7M729 | |||||||||||
| RefSeq (mRNA) | NM_001142348.1 | NM_001013390.2 | |||||||||||
| RefSeq (protein) | NP_001135820.1 | NP_001013408.1 | |||||||||||
| Location (UCSC) | Chr 11: 118 – 118.02 Mb |
Chr 9: 44.95 – 44.96 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Sodium channel, also known as SCN4B is a protein which in humans is encoded by the SCN4B gene.[1]
SCN4B is a sodium channel associated with long QT syndrome.[2]
Contents |
See also [link]
References [link]
- ^ "Entrez Gene: sodium channel". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6330.
- ^ Medeiros-Domingo A, Kaku T, Tester DJ, Iturralde-Torres P, Itty A, Ye B, Valdivia C, Ueda K, Canizales-Quinteros S, Tusié-Luna MT, Makielski JC, Ackerman MJ (July 2007). "SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome". Circulation 116 (2): 134–42. DOI:10.1161/CIRCULATIONAHA.106.659086. PMID 17592081.
Further reading [link]
- Delgado P, GarcÃa-Zueco JC, Rubio-Félix D, Giralt M (1992). "[Idiopathic thrombocytopenic purpura: present knowledge and future expectations]". Sangre 37 (6): 449–56. PMID 1293796.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
- Yu FH, Westenbroek RE, Silos-Santiago I, et al. (2003). "Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2.". J. Neurosci. 23 (20): 7577–85. PMID 12930796.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. DOI:10.1101/gr.4039406. PMC 1356129. PMID 16344560. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Webb J, Wu FF, Cannon SC (2009). "Slow inactivation of the NaV1.4 sodium channel in mammalian cells is impeded by co-expression of the beta1 subunit.". Pflugers Arch. 457 (6): 1253–63. DOI:10.1007/s00424-008-0600-8. PMID 18941776.
External links [link]
- GeneReviews/NIH/NCBI/UW entry on Romano-Ward Syndrome
- SCN4B+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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