S100 calcium-binding protein P (S100P) is a protein that in humans is encoded by the S100P gene.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer.
S100P has been shown to interact with EZR and RAGE. The interactions between S100P and RAGE disrupted by cromolyn and pentamidine.
Where are those happy days, they seem so hard to find
I tried to reach for you, but you have closed your mind
Whatever happened to our love
I wish I understood
It used to be so nice, it used to be so good
So when you're near me, darling can't you hear me
S. O. S.
The love you gave me, nothing else can save me
S. O. S.
When you're gone
How can I even try to go on
When you're gone
Though I try how can I carry on
You seem so far away though you are standing near
You made me feel alive, but something died I fear
I really tried to make it out
I wish I understood
What happened to our love, it used to be so good
So when you're near me, darling can't you hear me
S. O. S.
The love you gave me, nothing else can save me
S. O. S.
When you're gone
How can I even try to go on
When you're gone
Though I try how can I carry on
So when you're near me, darling can't you hear me
S. O. S.
And the love you gave me, nothing else can save me
S. O. S.
When you're gone
How can I even try to go on
When you're gone
Though I try how can I carry on
When you're gone
How can I even try to go on
When you're gone
Though I try how can I carry on