Runyon classification

The Runyon classification of nontuberculous mycobacteria based on the rate of growth, production of yellow pigment and whether this pigment was produced in the dark or only after exposure to light.

It was introduced by Ernest Runyon in 1959.

On these bases, the nontuberculous mycobacteria are divided into four groups:

Slowly growing Mycobacteria

The first three groups are classified as "Slowly growing Mycobacteria".

Runyon I: Photochromogens

Runyon I organisms (photochromogens) are slow growing, and produce a yellow-orange pigment when exposed to light. The group includes Mycobacterium kansasii, Mycobacterium marinum, Mycobacterium asiaticum, and Mycobacterium simiae. Mycobacterium szulgai is a photochromogen when grown at 24 degrees, and a scotochromogen at 37 degrees.

Runyon II: Scotochromogens

Runyon II organisms (scotochromogens) are slow-growing and produce a yellow-orange pigment regardless of whether they are grown in the dark or the light. The group includes Mycobacterium gordonae and Mycobacterium scrofulaceum, among others. Mycobacterium szulgai is a scotochromogen when grown at 37 degrees, as mentioned above.