TMC

TMC may stand for:

Companies and brands

TMC2

Transmembrane channel-like protein 2 is a protein that in humans is encoded by the TMC2 gene.

Function

This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, expression in the inner ear suggests that it may be crucial for normal auditory function.

Clinical significance

Mutations in this gene may underlie hereditary disorders of balance and hearing.

References

Further reading

TMC6

Transmembrane channel-like protein 6 is a protein that in humans is encoded by the TMC6 gene.In vivo, TMC6 and its homolog TMC8, interact and form a complex with the zinc transporter 1 (SLC30A1) and localize mostly to the endoplasmic reticulum, but also to the nuclear membrane and Golgi apparatus.

Inactivating mutations in TMC6 or TMC8 have been implicated as the genetic cause of the rare skin disorder epidermodysplasia verruciformis, which is characterized by abnormal susceptibility to human papillomaviruses (HPVs) of the skin resulting in the growth of scaly macules and papules, particularly on the hands and feet.

References

Further reading

Run

Run(s) or RUN may refer to:

Sports and games, and general uses

Geography and topography

People

Run!

"Run!" is the fifteenth episode of the first season of the NBC science fiction drama series Heroes. Regular cast members Milo Ventimiglia (Peter Petrelli) and Santiago Cabrera (Isaac Mendez) do not appear in this episode.

Plot

Meredith calls and informs Nathan that their daughter Claire is still alive. Aware that the scandal could ruin his political future, Nathan gives Meredith $100,000 for her silence. Elsewhere, Mrs. Bennet's health deteriorates, causing the rift between Claire and Mr. Bennet, since she blames him for her mother's condition. He grounds her after learning she skipped school, prompting Claire to be more outraged. Claire later shows up at Meredith's trailer, hoping that her biological father could help Mrs. Bennet. Meredith tells Claire that he will only disappoint her, and Meredith herself is going back to Mexico. She takes a picture of Claire as remembrance, which she later shows to a visiting Nathan. Meredith offers to introduce them, but Nathan refuses - this crushes an eavesdropping Claire. Visibly upset, Nathan gets inside his limo and leaves. Claire hurls a stone at his rear window in anger.

Run 2

"Run 2" was New Order's third and final single from their 1989 album Technique. The album version was listed as simply "Run".

Overview

"Run 2" was remixed by Scott Litt from the version on Technique, hence the appendage of "2" to the title. The main difference is that the song has been made more radio-friendly by editing down most of the long instrumental run-out and appending it with a final repeat of the chorus. Litt's mix strips back much of the echo and layers of synthesizers, and in place centres the mix on Sumner's vocal and the bass guitar of Peter Hook. Despite the effort taken to produce a radio single, only 20,000 of the Factory 12" release were ever pressed. 500 7-inch records were also pressed, for promotional use. The single was only released in the UK.

John Denver's publishing company filed a lawsuit, alleging that the guitar break in "Run" too closely resembled Denver's "Leaving on a Jet Plane". The case was settled out of court. The song has since been credited to New Order and John Denver.