Rnd Protein

Rnd is a subclass of the Rho family of GTPases^[1], and includes:

Functions include downregulation of stress fibres and focal adhesions.

References [link]

^ Ridley A. (2006). "Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking". Trends Cell Biol 16 (10): 522–9. DOI:10.1016/j.tcb.2006.08.006. ISSN 0962-8924. PMID 16949823.

3.6.3

Cu++ (3.6.3.4)	Menkes/ATP7A Wilson/ATP7B

Ca+ (3.6.3.8)	SERCA (ATP2A1, ATP2A2, ATP2A3) Plasma membrane (ATP2B1, ATP2B2, ATP2B3, ATP2B4) SPCA (ATP2C1, ATP2C2)

Na+/K+ (3.6.3.9)	ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4

H+/K+ (3.6.3.10)	ATP4A

Other P-type ATPase	ATP8B1 ATP10A ATP11B ATP12A ATP13A2 ATP13A3

3.6.4

3.6.5.1: Heterotrimeric G protein	G_αs G_αi (GNAI1, GNAI2, GNAI3) G_αq/11 (GNAQ, GNA11) G_α12/13 (GNA12, GNA13) Transducin (GNAT1, GNAT2)

3.6.5.2: Small GTPase > Ras superfamily	Rho family of GTPases: Cdc42 (CDC42, TC10, TCL) RhoUV (RhoU, RhoV) Rac (Rac1, 2, 3, RhoG) RhoBTB (1, 2) RhoH Rho (A, B, C) Rnd (1, 2, 3) RhoDF (RhoF, RhoD) other: Ras (HRAS, KRAS, NRAS) Rab (RAB23, RAB27) Arf (ARF6, SAR1B, ARL13B, ARL6) Ran Rheb Rap

3.6.5.3: Protein-synthesizing GTPase	Prokaryotic (IF-2, EF-Tu, EF-G) Eukaryotic

3.6.5.5-6: Polymerization motors	Dynamin Tubulin

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