Richard Henderson

Richard Henderson, Rick Henderson, Rickey Henderson, Dick Henderson or Dickie Henderson may refer to:

See also

Richard Henderson (biologist)

Richard Henderson FRS (born 19 July 1945) is a Scottish molecular biologist and biophysicist and pioneer in the field of electron microscopy of biological molecules.

Career

Starting in 1975 with Nigel Unwin, Henderson studied the structure of the membrane protein bacteriorhodopsin (bR) by electron microscopy. A seminal paper in Nature by Henderson and Unwin (1975) established a low resolution structural model for bR showing the protein to consist of 7 transmembrane helices. This paper was important for a number of reasons, not the least of which was that it showed that membrane proteins had well defined structures and that transmembrane alpha-helices could occur. After 1975 Henderson worked without Unwin on the structure of bR.

In 1990 Henderson published an atomic model of bR by electron crystallography in the Journal of Molecular Biology. This model was the second ever atomic model of a membrane protein. The techniques Henderson developed for electron crystallography are still in use. More recently, Dr. Henderson has devoted his attention to single particle electron microscopy: he was an early proponent of the idea that single particle EM is capable of determining atomic resolution models for proteins, explained in a 1995 paper in Quarterly Reviews of Biophysics. He made seminal contributions to many of the approaches used in single particle EM, including pioneering the development of direct electron detectors that recently allowed single particle cryo-EM to achieve this goal.

Richard Henderson (jurist)

Richard Henderson (1734–1785) was an American pioneer and merchant who attempted to create a colony called Transylvania just as the American Revolutionary War was starting. After the Declaration of Independence (1776) and the organization of the state government in North Carolina, he was re-elected judge, but was prevented from accepting that position by his participation in a scheme organized under the name of the Transylvania Compact.

Early life

Henderson was born in Hanover County, Virginia Colony. In 1762, he moved to Granville County, North Carolina, studied law, was admitted to the bar, practiced law, and in 1769 was appointed judge of the Superior Court. He was the presiding judge who condemned captured tax resistors to death during the War of the Regulation. Viewed as a member of the gentry, he had been a target of Regulator violence. He was a member of a Church of England parish in Williamsboro during this time.

In the company of wilderness explorers

In 1772, surveyors placed the land officially within the domain of the Cherokee tribe, who required negotiation of a lease with the settlers. Tragedy struck as the lease was being celebrated, when a Cherokee warrior was murdered by a white man. Robertson's skillful diplomacy made peace with the irate Native Americans, who threatened to expel the settlers by force if necessary.