¿¡Revolución!?
¿¡Revolución!? is a 2006 political documentary directed by Quebec journalist and filmmaker Charles Gervais. It examines the Bolivarian Revolution led by Venezuelan President Hugo Chávez. It was produced by Télé-Québec, the Quebec government's public television network.
As part of the Rencontres internationales du documentaire de Montréal film festival, first screenings occurred on November 10 and 14, 2006 at the Cinéma ONF in Montreal. The general opening happened on December 8, 2006, at Cinéma Ex-Centris, also in Montreal. This version showed the original Spanish spoken by the subjects, as well as narration and subtitles in French.
Production
In April 2005, director Charles Gervais heard of the news that Hugo Chávez decided to distribute one million free copies of major 17th century Spanish novel Don Quixote de la Mancha to Venezuelan citizens. This gave him the inspiration to fly to Venezuela and examine from within this "revolution" in the making. Also, after filming the medium-length documentary Quand la vie est un rêve on the Haitian youth, Gervais wished to focus on something more positive.
Revolución
Revolución (English: Revolution) is the sixth studio album by Spanish power metal band WarCry. This was the band's first release after La Quinta Esencia and with the new line-up. Víctor García stated on the band's website that the name of the songs had pretty much nothing to do with the meaning of the lyrics, e.g. "El Cazador" (The Hunter) "doesn't talk about the profession of being hunter, but the word's darker side, where killer would be the right way to describe it.
Track listing
Credits
Band
Revolución (song)
"Revolución" (Eng.: Revolution) is the title of the fifth single released by Enrique Iglesias from his second album, Vivir.
Song information
The track was written by Chein García-Alonso, who also wrote the #1 hit "Experiencia Religiosa" for Iglesias. This single became the first song released in United States not to peak at number 1 on the Billboard Hot Latin Tracks chart, breaking the string of eight consecutive number ones ("Si Tú Te Vas", "Experiencia Religiosa", "Por Amarte", "No Llores Por Mí", "Trapecista", "Enamorado Por Primera Vez", "Sólo En Tí" and "Miente").
Chart performance
The track debuted on the United States Billboard Hot Latin Tracks chart at number 12 on 10 October 1997 and peaked at number 6 two weeks later on 25 October 1997.
References
MDM
MDM may refer to:
In business
In entertainment
In science and technology
Mdm2
Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene. Mdm2 is an important negative regulator of the p53 tumor suppressor. Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor suppressor and an inhibitor of p53 transcriptional activation.
Discovery and expression in tumor cells
The murine double minute (mdm2) oncogene, which codes for the Mdm2 protein, was originally cloned, along with two other genes (mdm1 and mdm3) from the transformed mouse cell line 3T3-DM. Mdm2 overexpression, in cooperation with oncogenic Ras, promotes transformation of primary rodent fibroblasts, and mdm2 expression led to tumor formation in nude mice. The human homologue of this protein was later identified and is sometimes called Hdm2. Further supporting the role of mdm2 as an oncogene, several human tumor types have been shown to have increased levels of Mdm2, including soft tissue sarcomas and osteosarcomas as well as breast tumors. The MDM2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functions. MDM2 supports the Polycomb-mediated repression of lineage-specific genes, independent of p53. MDM2 depletion in the absence of p53 promoted the differentiation of human mesenchymal stem cells and diminished clonogenic survival of cancer cells. Most of the MDM2-controlled genes also responded to the inactivation of the Polycomb Repressor Complex 2 (PRC2) and its catalytic component EZH2. MDM2 physically associated with EZH2 on chromatin, enhancing the trimethylation of histone 3 at lysine 27 and the ubiquitination of histone 2A at lysine 119 (H2AK119) at its target genes. Removing MDM2 simultaneously with the H2AK119 E3 ligase Ring1B/RNF2 further induced these genes and synthetically arrested cell proliferation.
MDM4
Protein Mdm4 is a protein that in humans is encoded by the MDM4 gene.
Function
The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2
Interactions
MDM4 has been shown to interact with E2F1,Mdm2 and P53.
