Return

Return may refer to:

In business, economics, and finance

In technology

In entertainment

Film

Return (2011 film)

Return is a 2011 independent film about an American reservist, wife and mother returning home from her tour of duty in the Middle East. The film was written and directed by Liza Johnson, and stars Linda Cardellini, Michael Shannon and John Slattery. It is Johnson's first feature-length film, and received good reviews at its premiere at the Cannes Film Festival Directors' Fortnight.

Synopsis

Kelli, returning from her military tour of duty in the Middle East, has high hopes for resuming her old life in her midwestern hometown. Her hopes are gradually dashed as her relationships with her family and friends suffer; they have moved on, and she cannot adjust. She is unable to provide the attention her children need, she quits her dull factory job, she discovers her husband Mike's infidelity, drinks with her friends, then is stopped by the police while driving under the influence. During her court-ordered therapy session, she meets Bud, a charming war veteran. She undergoes a gradual breakdown, but persists in her efforts to reestablish her life.

Returning

In retail, a return is the process of a customer taking previously purchased merchandise back to the retailer, and in turn receiving a refund in the original form of payment, exchange for another item (identical or different), or a store credit.

Many retailers will accept returns provided that the customer has a receipt as a proof of purchase, and that certain other conditions, which depend on the retailer's policies, are met. These may include the merchandise being in a certain condition (usually resellable if not defective), no more than a certain amount of time having passed since the purchase, and sometimes that identification be provided (though usually only if a receipt is not provided). In some cases, only exchanges or store credit are offered, again usually only without a receipt, or after an initial refund period has passed. Some retailers charge a restocking fee for non-defective returned merchandise, but typically only if the packaging has been opened.

While retailers are not usually required to accept returns, laws in many places require retailers to post their return policy in a place where it would be visible to the customer prior to purchase.

Hughes Mining Barge

The Hughes Mining Barge, or HMB-1, is a submersible barge about 99 m (324 ft) long, 32 m (106 ft) wide, and more than 27 m (90 ft) tall. The HMB-1 was originally developed as part of Project Azorian (more widely, but erroneously, known as "Project Jennifer"), the top-secret effort mounted by the Central Intelligence Agency to salvage the remains of the Soviet submarine K-129 from the ocean floor.

The HMB-1 was designed to allow the device that would be used to grasp and lift the submarine to be constructed inside the barge and out of sight, and to be installed in the Glomar Explorer in secrecy. This was done by towing the HMB-1, with the capture device inside, to a location near Catalina Island (off the coast of California), and then submerging it onto stabilizing piers that had been installed on the seafloor. The Glomar Explorer was then maneuvered over the HMB-1, the retractable roof was opened, and the capture device lifted into the massive "moon pool" of the ship, all within clear sight of people on the beach.

HMB-45

HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for human melanoma black 45. It is used in anatomic pathology as a marker for such tumors. The specific antigen recognized by HMB-45 is now known as Pmel 17.

HMB-45 was discovered by Drs. Allen M. Gown and Arthur M. Vogel in 1986. The antibody was generated to an extract of melanoma. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity.

In a study to determine diagnostic usefulness of specific antibodies used to identify melanoma, HMB-45 had a 92% sensitivity when used to identify melanoma. The antibody also reacts positively against junctional nevus cells and fetal melanocytes.

Despite this relatively high sensitivity—HMB-45 does have its drawbacks. HMB-45 can be detected in only 50-70% of melanomas. HMB-45 does not react well against intradermal nevi, normal adult melanocytes, spindle cell melanomas and desmoplastic melanomas. HMB-45 is nonreactive with almost all non-melanoma human malignancies, with the exception of rare tumors showing evidence of melanogenesis (e.g., pigmented schwannoma, clear cell sarcoma) or tumors associated with tuberous sclerosis complex (angiomyolipoma and lymphangiomyoma).