Revue des Études Juives
Revue des Études Juives is a French quarterly academic journal of Jewish studies, established in July 1880 at the École pratique des hautes études, Paris by the Société des Études Juives. The founding editor was Isidore Loeb; after his death it was edited by Israel Lévi. It is currently published by Peeters Publishers. The journal covers research and prints unpublished texts concerning Judaism, among others documents relative to the history of the French Jews. Nearly every issue also contains a special bibliographical section devoted to reviews of current works on Judaism.
Abstracting and indexing
The journal is abstracted and indexed in:
References
External links
CRM
CRM may refer to:
Sales and marketing
People
Art, entertainment, and media
Companies and institutions
Management
Resource management
CRM197
CRM197 is a non-toxic mutant of diphtheria toxin, currently used as a carrier protein for polysaccharides and haptens to make them immunogenic.
Description
CRM197 is a genetically detoxified form of diphtheria toxin. A single mutation at position 52, substituting glutamic acid for glycine, causes the ADP-ribosyltransferase activity of the native toxin to be lost. The structural basis for the lack of CRM197 toxicity has recently been elucidated. CRM197 is widely used as a carrier protein for conjugate vaccines. An advantage of CRM197 over toxoided proteins is that, because it is genetically detoxified, it retains its full complement of lysine amines for conjugation. There is also evidence suggesting that, compared with tetanus toxoid, there is less carrier-induced suppression of the immune response, especially when there are many individual polysaccharides linked to the same carrier protein. A summary of the uses and properties of CRM197 has been published. CRM197, like diphtheria toxin, is a single polypeptide chain of 535 amino acids (58.4 kD) consisting of two subunits (linked by disulfide bridges).
Podcasts:
