Rabí

Rabí is a village and municipality (obec) in Klatovy District in the Plzeň Region of the Czech Republic.

The municipality covers an area of 14.29 square kilometres (5.52 sq mi), and has a population of 468 (as at 2 October 2006).

Rabí lies approximately 28 kilometres (17 mi) south-east of Klatovy, 55 km (34 mi) south of Plzeň, and 106 km (66 mi) south-west of Prague.

History

Until 1918, the village was part of the Austrian monarchy (Austria side after the compromise of 1867), in the Strakonitz (Strakonice) district, one of the 94 Bezirkshauptmannschaften in Bohemia. A post-office was opened in 1869.

References

Rab (surname)

Rab is the surname of:

Rab (G-protein)

The Rab family of proteins is a member of the Ras superfamily of monomeric G proteins. Approximately 70 types of Rabs have now been identified in humans. Rab GTPases regulate many steps of membrane traffic, including vesicle formation, vesicle movement along actin and tubulin networks, and membrane fusion. These processes make up the route through which cell surface proteins are trafficked from the Golgi to the plasma membrane and are recycled. Surface protein recycling returns proteins to the surface whose function involves carrying another protein or substance inside the cell, such as the transferrin receptor, or serves as a means of regulating the number of a certain type of protein molecules on the surface.

Function

Rab proteins are peripheral membrane proteins, anchored to a membrane via a lipid group covalently linked to an amino acid. Specifically, Rabs are anchored via prenyl groups on two cysteines in the C-terminus. Rab escort proteins (REPs) deliver newly synthesized and prenylated Rab to its destination membrane by binding the hydrophobic, insoluble prenyl groups and carrying Rab through the cytoplasm. The lipid prenyl groups can then insert into the membrane, anchoring Rab at the cytoplasmic face of a vesicle or the plasma membrane. Because Rab proteins are anchored to the membrane through a flexible C-terminal region, they can be thought of as a 'balloon on a string'.