RTI-121
(–)-2β-Carboisopropoxy-3β-(4-iodophenyl)tropane (RTI-121, IPCIT) is a stimulant drug used in scientific research, which was developed in the early 1990s. RTI-121 is a phenyltropane based, highly selective dopamine reuptake inhibitor and is derived from methylecgonidine. RTI-121 is a potent and long-lasting stimulant, producing stimulant effects for more than 10 hours after a single dose in mice which would limit its potential uses in humans, as it might have significant abuse potential if used outside of a medical setting. However RTI-121 occupies the dopamine transporter more slowly than cocaine, and so might have lower abuse potential than cocaine itself.
Uses
RTI-121 is mainly used in scientific research into the dopamine reuptake transporter. It is more selective for the dopamine transporter than other DAT radioligands such as β-CIT, and so has less nonspecific binding and produces "cleaner" images. Various radiolabelled forms of RTI-121 (with different radioactive isotopes of iodine used depending on the application) are used in both humans and animals to map the distribution of dopamine transporters in the brain.
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Dead Reckoning
by: RattYou know you're livin' a lie when you just can't win
Pulling in first prize ain't gonna give you a break
You know I'm kickin' back, I had a broken wing
Me and my shadow are the next best thing
I need someone
You know it might take more than you give to me
Are you gun-shy, are you listening?
What we got here is dead reckoning
And take me in for the night in the right time zone
We'll do what you like, make a left turn home
I put out the light, you're turnin' way too red
No stop sign straight up ahead
You need so much
So much sympathy
That's more than I can say
You know it's not too late
Are you gun-shy, are you listening?
What we got here is dead reckoning
And if it feels good, we'll do it again
See your way clear, dead reckoning
Tell me why, tell me why
Are you listening?
Are you listening?
Are you listening?
Are you listening?
You mean so much
So much to me
That's more than I can say
You know it's not too late
Are you gun-shy, are you listening?
What we got here is dead reckoning
And if it feels good, we'll do it again
See your way clear, dead reckoning, yeah
What we got here is dead reckoning