RPL10
60S ribosomal protein L10 is a protein that in humans is encoded by the RPL10 gene.
Function
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L10E family of ribosomal proteins. It is located in the cytoplasm. In vitro studies have shown that the chicken protein can bind to c-Jun and can repress c-Jun-mediated transcriptional activation, but these activities have not been demonstrated in vivo. This gene was initially identified as a candidate for a Wilms tumor suppressor gene, but later studies determined that this gene is not involved in the suppression of Wilms tumor. This gene has been referred to as 'laminin receptor homolog' because a chimeric transcript consisting of sequence from this gene and sequence from the laminin receptor gene was isolated; however, it is not believed that this gene encodes a laminin receptor. Transcript variants utilizing alternative polyA signals exist. The variant with the longest 3' UTR overlaps the deoxyribonuclease I-like 1 gene on the opposite strand. This gene is co-transcribed with the small nucleolar RNA gene U70, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Podcasts:
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by Sesame Street
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by HIM
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by Scooter
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by Sinner
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by Billy Idol
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by Heaven's Gate
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by Dope
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by Kill Hannah
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by Children Of Bodom
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by Dillinger Escape Plan
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by Drowning Pool
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by Drowning Pool
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by Black Veil Brides
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by Assorted Jellybeans
Rebel L
by: Sesame StreetBilly Idle: Last night as I was lyin'
Just loungin' in my bed,
Heard such a loony howling',
Stood my hair up on my head.
Lunged over to the window,
Flipped the floodlight right on.
Hey, there's a letter L
On the loose,
Leaping across my lawn!
I heard the letter L
Let out a 'luh-luh-luh.'
The little rebel L,
He cried, 'Luh-luh-luh.'
Luh-luh-luh!'
I heard the letter L
Let out a 'luh-luh-luh.'
The little rebel L,
He went, 'Luh-luh-luh,
LUH-LUH-LUH!'
Rebel L!
He said, 'You gotta listen,
See, I'm a lean, mean lad.
Don't like to stand for 'lacy
Little lamb' or 'lilly pad!'
Just wanna live for loudness,
And don't say I'm too young.
I was born to go luh-luh-luh
At the top of my luh-luh-lungs!'
I heard the letter L
Let out a 'luh-luh-luh.'
The little rebel L,
He cried, 'Luh-luh-luh.'
Luh-luh-luh!'
I heard the letter L
Let out a 'luh-luh-luh.'
The little rebel L,
He went, 'Luh-luh-luh,
LUH-LUH-LUH!'
Rebel L!
Leaned out a little lower,
'Leapin' lizards!' I yelled,
'You gotta learn a lesson,
Hey, it's late, get lost, rebel L
You're wakin' up the neighbors.
Please leave us in peace.
Looks like you're outta luck,
Letter L,
Here come the pol-luh-luh-lice!'
Policewoman: Hey, little letter L,
You're too loud, loud, loud.
We know you're lost and lonely
Without a crowd, crowd,
Crowd, crowd.
But listen, letter L,
We got laws, laws, laws!
Rebel L: I'm just a rebel L
Without a cause, cause, cause!
A rebel L!
I'm just a rebel L!
You know I'm just a rebel L!
You know I'm just a rebel L!
I'm just a rebel L!