MIDI

MIDI (/ˈmɪdi/; short for Musical Instrument Digital Interface) is a technical standard that describes a protocol, digital interface and connectors and allows a wide variety of electronic musical instruments, computers and other related devices to connect and communicate with one another. A single MIDI link can carry up to sixteen channels of information, each of which can be routed to a separate device.

MIDI carries event messages that specify notation, pitch and velocity, control signals for parameters such as volume, vibrato, audio panning, cues, and clock signals that set and synchronize tempo between multiple devices. These messages are sent via a MIDI cable to other devices where they control sound generation and other features. This data can also be recorded into a hardware or software device called a sequencer, which can be used to edit the data and to play it back at a later time.

MIDI technology was standardized in 1983 by a panel of music industry representatives, and is maintained by the MIDI Manufacturers Association (MMA). All official MIDI standards are jointly developed and published by the MMA in Los Angeles, California, US, and for Japan, the MIDI Committee of the Association of Musical Electronics Industry (AMEI) in Tokyo.

Riegel mine 43

The Riegel mine 43 or (Sprengriegel/R.Mi. 43) is a German steel cased anti-tank bar mine used during the Second World War. The mine is a long thin rectangle. It consists of a lower and upper metal tray, and an internal metal-cased explosive block. It uses two ZZ42 fuzes inserted into either end of the internal block, although it can be used with an additional pressure fuze on the top. The mine is similar to the Italian B-2 mine. A variant, the Riegel mine 44 was also produced with a different fuze. Approximately 3,051,400 were produced between 1943 and 1945.

Riegelmines are almost impossible to disarm because wires in the fuze mechanisms become corroded, which makes them highly unstable. As a result, the mine becomes extremely sensitive to the smallest disturbance, and therefore can easily detonate simply by touching it. The situation is further complicated by the fact that Riegel mines can be fitted with up to three anti-handling devices. The recommended render-safe procedure for any Riegel mine is to destroy it in situ by detonating a small explosive charge next to it.

RMI1

RecQ-mediated genome instability protein 1 is a protein that in humans is encoded by the RMI1 gene.

Meiosis

During meiosis in budding yeast Saccharomyces cerevisiae, TOP3 (a type I topoisomerase) and its accessory factor RMI1 form a heterodimer that functions to allow passage of one DNA single strand through another. The TOP3-RMI1 heterodimer associates with Sgs1 (Bloom helicase ortholog) to form a complex that catalyzes dissolution of double Holliday junctions. Furthermore, the TOP3-RMI1 heterodimer participates in all meiotic recombination functions associated with Sgs1, most significantly as an early recombination intermediate chaperone, promoting regulated crossover and non-crossover recombination and preventing accumulation of aberrant recombination intermediates. In particular, the TOP3-RMI1–SGS1 complex promotes early formation of non-crossover recombinants during meiosis.

References

Further reading