RHEB
GTP-binding protein Rheb also known as Ras homolog enriched in brain (RHEB) is a protein that in humans is encoded by the RHEB gene.
Function
Rheb is a recently discovered member of the Ras superfamily that may be involved in neural plasticity. This function is novel and not typically associated with the Ras proteins. Deficiency of this protein in the forebrain of mice embryos is associated with decreased myelinization due to decrease of mature oligodendrocytes.
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin / TOR / S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Podcasts:
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by Rippa
Queen of Denial
by: RubyI will clean and cover my windows
'Cos I don't want to see where the wind blows
I'll love it, I'll covet another one's idol
Because I am the queen of denial
I'll love it, I'll love it
I'll love it, I'll love it
The ego is the master of psyche
And envy tastes sweeter than grey meat
I'll love it and learn to follow behind all
Because I am the king of denial
I'll love it, I'll love it
I'll love it, I'll love it
The back will snap from burdens of envy
And I'll forget the mould who set me
I'll love it, and shove it from proof to trial
Because I carry the weight of denial
I'll love it, I'll love it
I'll love it, I'll love it
Everybody loves to want to
Everybody wants to need to
Everybody needs to be
To be somebody else
Everybody loves to want to
Everybody wants to need to
Everybody needs to be
To be somebody else
Everybody loves to want to
Everybody wants to need to
Everybody needs to be
To be somebody else
Everybody loves to want to
Everybody wants to need to
Everybody needs to be