RGS7

Regulator of G-protein signaling 7 is a protein that in humans is encoded by the RGS7 gene.

RGS7 is highly enriched in the brain where it acts as a universal inhibitor of Gi/o-coupled GPCR. RGS7 is a GTPase-activating protein (GAP). It accelerates the GTP hydrolysis on G proteins determining their fast inactivation and acting as intracellular antagonists of GPCR signaling.

Interactions

RGS7 has been shown to interact with:

  • GNB5,
  • GPR158,
  • PKD1, and
  • SNAPAP.
  • References

    Further reading


    Podcasts:

    PLAYLIST TIME:

    Rex's

    by: James Mcmurtry

    ride the blue wind high and free
    she'll lead you down to misery
    leave you low come time to go
    alone and low as low can be
    if I had a nickle I'd find a game
    if I won a dollar I'd make it rain
    if it rained an ocean I'd drink it dry
    and lay me down dissatisfied
    tell my sister I said so long
    tell my mother I did no wrong
    tell my brother to watch his own
    tell my friends to mourn me none
    legs to walk and thoughts to fly
    eyes to laugh and lips to cry
    a restless tongue to classify
    all born to grow and grown to die
    chained across the face of time
    feeling full of foolish rhyme
    there aint no dark 'til something shines
    I'm bound to leave this dark behind
    ride the blue wind high and free
    she'll lead you down to misery
    leave you low come time to go




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