RCOR1

REST corepressor 1 also known as CoREST is a protein that in humans is encoded by the RCOR1 gene.

Function

This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor).

Interactions

RCOR1 has been shown to interact with

  • HDAC1,
  • HDAC2,
  • HMG20B,
  • REST and
  • PHF21A.
  • References

    Further reading

    This article incorporates text from the United States National Library of Medicine, which is in the public domain.


    Podcasts:

    PLAYLIST TIME:
    ×