RAD51C
RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene.
Function
The RAD51C protein is one of five paralogs of RAD51, including RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 and XRCC3. They each share about 25% amino acid sequence identity with RAD51 and each other.
The RAD51 paralogs are all required for efficient DNA double-strand break repair by homologous recombination and depletion of any paralog results in significant decreases in homologous recombination frequency.
RAD51C forms two distinct complexes with other related paralogs: BCDX2 (RAD51B-RAD51C-RAD51D-XRCC2) and CX3 (RAD51C-XRCC3). These two complexes act at two different stages of homologous recombinational DNA repair. The BCDX2 complex is responsible for RAD51 recruitment or stabilization at damage sites. The BCDX2 complex appears to act by facilitating the assembly or stability of the RAD51 nucleoprotein filament.
The CX3 complex acts downstream of RAD51 recruitment to damage sites. The CX3 complex was shown to associate with Holliday junction resolvase activity, probably in a role of stabilizing gene conversion tracts.
Podcasts:
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by Atmosphere
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by Tyga
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by Style Council
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by Goodie Mob
3.2 Red Dog
by: Atmosphere(one of those nights
warm beer, cold women
I just don't fit in)
It goes 1, it goes 2, it goes
3-2 red dog in the hoodie
too much "person" in your "ality", the friction could be
Should we continue with dialogue as I study these new faces
I would fix my shoe laces, but the room place was
Shoes cut loose at the front door,
got dirty socks, I'm on the floor
and thoughts is what I hunt for
Driftin in and out of conversations I know nothing about
Fuck your topics, I didn't come to see you
But yo I'm here, might as well make the worst of this warm shitty beer
and I'm nursin it, and cursin it
I'm sick of it, but still grippin it and sippin it
Hopin it'll dull the pain of the sight of your lips flippin' shit
So here I sit, inside my atmosphere
I don't know a single motherfucker here,
but maybe that's my fear
Pull out my notebook and let go
Intro-spectro cep,
Not so pleased to meet you,
and I hate techno
I only came to see the girl that lives here,