Quinine is a medication used to prevent and treat malaria and to treat babesiosis. This includes to treat malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available. While used for restless legs syndrome it is not recommended for this purpose. It can be taken by mouth or used intravenously. Malaria that is resistant to quinine occur in certain areas of the world.
Common side effects include headache, ringing in the ears, trouble seeing, and sweating. More severe side effects include deafness, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy causes harm to the baby, use to treat malaria during pregnancy is still recommended. How it works is not entirely clear.
Quinine was first isolated in 1820 from the bark of the cinchona tree. Extracts from the bark has been used to treat malaria since at least 1632. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. The wholesale price is about 1.70 to 3.40 USD per course of treatment.
Quinine is the third studio album released by rapper, Nine. It was released both digitally and on CD on April 9, 2009, (the only difference being that the CD version included a bonus track entitled "U Don't Want That") with Nine serving as an executive producer as well as writing and arranging all the tracks on the album. It is his first album in 13 years, his last effort being 1996's Cloud 9.