Quetiapine

Quetiapine, marketed as Seroquel, is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder, and along with an antidepressant to treat major depressive disorder. It is also sometimes used as a sleep aid because of its sedating effect but this use is not recommended.

Annual sales are approximately $1.3 billion worldwide. Quetiapine was developed by AstraZeneca from 1992 to 1996. It was first approved by the FDA in 1997. There are now several generic versions.

Medical uses

Quetiapine is primarily used to treat schizophrenia or bipolar disorder.

Schizophrenia

A second Cochrane Review comparing quetiapine to typical antipsychotics concluded that quetiapine