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Pugnac
Pugnac is a commune in the Gironde department in Aquitaine in southwestern France.
Population
See also
References
PUGNAc
PUGNAc is a 1,5-hydroximolactone, acting as an inhibitor of a variety of N-acetylhexosaminidases. It was long thought that increased levels of O-GlcNAc in human cells lead to Type II diabetes. O-GlcNAc levels were artificially raised with PUGNAc, which inhibits O-GlcNAcase, a beta-exo-N-acetylhexosaminidase which cleaves beta-O-linked-N-acetylglucosamine residues from glycoproteins. As a result of this inhibition, a type II diabetic phenotype was observed. Recent pharmacological studies using a more selective O-GlcNAcase inhibitor did not see this effect. However, genetic manipulation of O-GlcNAc levels is consistent with the effects observed by PUGNAc, namely insulin resistance upon elevation of O-GlcNAc levels.
Fictional references
PUGNAc was used by Michael Scofield in the television series Prison Break to keep his blood sugar level high to appear diabetic and to be resistant to insulin shots he was receiving from the infirmary. He wanted this to get unlimited access to the infirmary building. Michael Scofield used PUGNAc to follow through with his escape plan.
Radio Stations - Pugnac
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Just Like A Pill
by: PinkI'm lyin' here on the floor where you left me
I think, I took too much
I'm cryin' here, what have you done?
I thought it would be fun
I can't stay on your life support, there's a shortage in the switch
I can't stay on your morphine, 'cuz its makin' me itch
I said, I tried to call the nurse again but she's being a little bitch
I think I'll get outta here, where I can
Run just as fast as I can
To the middle of nowhere
To the middle of my frustrated fears
And I swear you're just like a pill
Instead of makin' me better, you keep makin' me ill
You keep makin' me ill
I haven't moved from the spot where you left me
This must be a bad trip
All of the other pills, they were different
Maybe I should get some help
I can't stay on your life support, there's a shortage in the switch
I can't stay on your morphine, 'cuz its makin' me itch
I said, I tried to call the nurse again but she's being a little bitch
I think I'll get outta here, where I can
Run just as fast as I can
To the middle of nowhere
To the middle of my frustrated fears
And I swear you're just like a pill
Instead of makin' me better, you keep makin' me ill
You keep makin' me ill
Run just as fast as I can
To the middle of nowhere
To the middle of my frustrated fears
And I swear you're just like a pill
Instead of makin' me better, you keep makin' me ill
You keep makin' me ill
I can't stay on your life support, there's a shortage in the switch
(Just like a pill)
I can't stay on your morphine, 'cuz its makin' me itch
(Just like a pill)
I said, I tried to call the nurse again but she's being a little bitch
(Just like a pill)
I think I'll get outta here, where I can
Run just as fast as I can
To the middle of nowhere
To the middle of my frustrated fears
(Frustrated, frustrated fears)
And I swear you're just like a pill
Instead of makin' me better, you keep makin' me ill
You keep makin' me ill
Run just as fast as I can
To the middle of nowhere
To the middle of my frustrated fears
(Frustrated fears)
And I swear you're just like a pill
(Just like a pill)
Instead of makin' me better, you keep makin' me ill
(Makin' me, makin' me ill)
You keep makin' me ill
Run just as fast as I can
To the middle of nowhere
To the middle of my frustrated fears
And I swear you're just like a pill
Instead of makin' me better, you keep makin' me ill
(Oh you keep makin' me ill)
You keep makin' me ill
Run just as fast as I can
To the middle of nowhere
To the middle of my frustrated fears