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Ptení
Ptení is a village and municipality (obec) in Prostějov District in the Olomouc Region of the Czech Republic.
The municipality covers an area of 18.51 square kilometres (7.15 sq mi), and has a population of 1,109 (as at 28 August 2006).
Ptení lies approximately 14 kilometres (9 mi) west of Prostějov, 25 km (16 mi) west of Olomouc, and 192 km (119 mi) east of Prague.
References
PTEN
PTEN may mean:
See also
PTEN (gene)
Phosphatase and tensin homolog (PTEN) is a protein that, in humans, is encoded by the PTEN gene. Mutations of this gene are a step in the development of many cancers. PTEN orthologs have been identified in most mammals for which complete genome data are available.
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin-like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating Akt/PKB signaling pathway.
Function
The PTEN protein is widely expressed throughout the body. PTEN protein acts as a phosphatase to dephosphorylate phosphatidylinositol (3,4,5)-trisphosphate (PtdIns (3,4,5)P3 or PIP3). PTEN specifically catalyses the dephosporylation of the 3` phosphate of the inositol ring in PIP3, resulting in the biphosphate product PIP2 (PtdIns(4,5)P2). This dephosphorylation is important because it results in inhibition of the AKT signaling pathway.
Radio Stations - Ptení
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Podcasts:
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by Jessica Simpson
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by Byzantine
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by N2U
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by Silent Sanctuary
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by Gruff Rhys
Between You & I
by: Jessica SimpsonBetween you and I,
And the starlight of the sky,
Nothin' and no one would ever know,
Galaxies high, you take me so fully,
As we jive through tonight,
Holdin' nothin' from eyes,
All I ever need, is you to take this crown,
Just lay me down,
All I have, is you to pull me through
This world that I'm in, my love,
Between you and I (Just you and I, Just you and I
Baby, Just can't stop lovin' you,
Your kisses, are haunting my head
Between you and I darlin',
Nothin' could get better baby,
I just love when you call me lady,
oh ya know that drives me crazy
Violets are blue,
'N' every color, brings remnants of you,
Reach up and touch what you can feel,
Captivated, so surreal,
Drowning inside,
Of your soul that runs so deep,
As I'm lying here beside you, Infatuated, I'm so weak
All I ever need, is you to take this crown,
Just lay me down,
All I have, is you to pull me through
This world that I'm in, my love,
Between you and I (Just you and I, Just you and I
Baby, Just can't stop lovin' you,
Your kisses, are haunting my head
Between you and I darlin',
Nothin' could get better baby,
I just love when you call me lady,
oh ya know that drives me crazy
Baby, please,
Say that you'll understand
That tonight, is a night, to love again,
Sweet memories,
of kisses we've blown in the wind,
And I'll cherish this quiet time we spend alone
Between you and I (Just you and I, Just you and I
Baby, Just can't stop lovin' you,
Your kisses, are haunting my head
Between you and I darlin',
Nothin' could get better baby,
I just love when you call me lady,