PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (disks large homolog 4) gene.
PSD-95 is a member of the membrane-associated guanylate kinase (MAGUK) family. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. PSD-95 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin, NMDA receptors, AMPA receptors, and potassium channels. It plays an important role in synaptic plasticity and the stabilization of synaptic changes during long-term potentiation.
Adobe Photoshop is a raster graphics editor developed and published by Adobe Systems for Windows and OS X.
Photoshop was created in 1988 by Thomas and John Knoll. Since then, it has become the de facto industry standard in raster graphics editing, such that the word "photoshop" has become a verb as in "to Photoshop an image," "photo shopping," and "photoshop contest," etc. It can edit and compose raster images in multiple layers and supports masks, alpha compositing and several color models including RGB, CMYK, Lab color space, spot color and duotone. Photoshop has vast support for graphic file formats but also uses its own PSD
and PSB
file formats which support all the aforementioned features. In addition to raster graphics, it has limited abilities to edit or render text, vector graphics (especially through clipping path), 3D graphics and video. Photoshop's featureset can be expanded by Photoshop plug-ins, programs developed and distributed independently of Photoshop that can run inside it and offer new or enhanced features.
PSD may refer to:
Steve Davison, better known as PSD, PSD Tha Drivah or Stevie Dee, is a rapper and producer from Vallejo, California, US, who is closely associated with the late Mac Dre and his record label, Thizz Entertainment.
PSD tha Drivah first appeared on Mac Dre's 1996 compilation entitled, ‘The Rompilation’, appearing on the track, "Menage A Trois" and producing the tracks, "Uninvited" and "Gumbo". After that he would appear on N2Deep's 1997 album entitled, ‘The Golden State’ and release his debut album, ‘Game Costs’. PSD tha Drivah would later release several more albums, 1999's ‘Bread Head’ and ‘What It Is’, 2002's ‘All I Want’, 2003's ‘You Ain't Heard of Me?’ and 2005's ‘The Guru’ and ‘PSD Classic’ before finally making it to the Billboard charts with 2007's ‘Da Bidness’, which was released with Messy Marv and Keak da Sneak.
PSD tha Drivah has roots from both Vallejo’s Crest Side neighborhood, as well as Mississippi. The rapper is known for his smooth harmonious voice and being a "playa. PSD tha Drivah has put out numerous mixtapes with DJ Ambush, called ‘Mixes And Renditions’. PSD tha Drivah is also known as "Playa Stevie Dee", PSD or "Tha Drivah" for his swagger and his excellent driving skills. PSD was close friends with Mac Dre; they formed a rap group called the Cutthoat Committee which also includes rapper Dubee. The group went on to record two albums ‘Turf Buccaneers’ and ‘Money Iz Motive’. The group disbanded due to the untimely death of Mac Dre.
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