Prestwick

Coordinates: 55°29′44″N 4°36′51″W / 55.495551°N 4.614160°W / 55.495551; -4.614160

Prestwick is a town in South Ayrshire on the south-west coast of Scotland, about 30 miles (50 km) south-west of Glasgow. It adjoins the larger town of Ayr, the centre of which is about 2 miles (3 km) south. It had a population of 14,934 at the 2001 census.

The town is served by Glasgow Prestwick Airport, which serves many European destinations as well as transatlantic and other international cargo flights.

The town was the first home of the Open Golf Championship, which was played on the Prestwick Old Course from 1860 to 1872.

Location

Prestwick lies on the south-west coast of Scotland, approximately 30 miles (50 km) to the south west of Glasgow. It adjoins the larger town of Ayr, the centre of which is approximately 2 miles (3 km) south. To the north of Prestwick is the small village of Monkton.

History

Prestwick's name comes from the Old English for, priest's farm: preost meaning "priest" and wic meaning "farm". The town was originally an outlying farm of a religious house.

Tolnaftate

Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions. It is supplied as a cream, powder, spray, and liquid aerosol. Tolnaftate is used to treat fungal conditions such as jock itch, athlete's foot and ringworm.

Mechanism

Although the exact mechanism of action is not entirely known, it is believed to inhibit squalene epoxidase, an important enzyme in the biosynthetic pathway of ergosterol (a key component of the fungal membrane) in a similar way to allylamines.

Uses

Tolnaftate has been found to be generally slightly less effective than azoles when used to treat tinea pedis (athlete's foot). It is, however, useful when dealing with ringworm, especially when passed from pets to humans.

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