Presenzano is a comune (municipality) in the Province of Caserta in the Italian region Campania, located about 60 kilometres (37 mi) north of Naples and about 40 kilometres (25 mi) northwest of Caserta. As of 31 December 2004, it had a population of 1,697 and an area of 31.7 square kilometres (12.2 sq mi).
Presenzano borders the following municipalities: Conca della Campania, Marzano Appio, Mignano Monte Lungo, Pratella, Sesto Campano, Tora e Piccilli, Vairano Patenora.