Puppy
A puppy is a juvenile dog. Some puppies can weigh 1–3 lb (0.45–1.36 kg), while larger ones can weigh up to 15–23 lb (6.8–10.4 kg). All healthy puppies grow quickly after birth. A puppy's coat color may change as the puppy grows older, as is commonly seen in breeds such as the Yorkshire Terrier. In vernacular English, puppy refers specifically to dogs while pup may often be used for other mammals such as seals, giraffes, guinea pigs, or even rats.
Development
Born after an average of 63 days of gestation, puppies emerge in an amnion that is bitten off and eaten by the mother dog. Puppies begin to nurse almost immediately. If the litter exceeds six puppies, particularly if one or more are obvious runts, human intervention in hand-feeding the stronger puppies is necessary to ensure that the runts get proper nourishment and attention from the mother. As they reach one month of age, puppies are gradually weaned and begin to eat solid food. The mother may regurgitate partially digested food for the puppies or might let them eat some of her solid food. The mother dog usually refuses to nurse at this stage, though she might let them occasionally nurse for comfort.
Puppy (Fluke album)
Puppy is the fifth and most recent album by British electronica group Fluke, first released in August 2003. The album contains a variety of genres, spanning from house to ambient and even including a Blues track, "Blue Sky".
The release of the album was significantly delayed by a change to the band's record label, switching from Virgin Records offshoot Circa to One Little Indian.
"Snapshot" was featured in Need for Speed: Underground while "Switch/Twitch" is featured in Need for Speed: Underground 2.
"Another Kind of Blues" is a 4:37 edit of previously released promotional single, Slap It (original length 10:19). Another version, renamed "Zion", was used for the underground rave scene in the 2003 film The Matrix Reloaded. Puppy's "Another Kind of Blues" is an entirely different song from the track of the same name included on the Xmas Demos.
The track "YKK" was used in the 2010 film The Experiment.
Four of the tracks on the album had previously been released in demo form on a Virgin Records promotional release from 2000 called Xmas Demos. The remaining tracks, "Liquid" and the original "Another Kind of Blues", did not make the final cut.
Puppy (Alice's Adventures in Wonderland)
The Puppy is a fictional character in Lewis Carroll's Alice's Adventures in Wonderland. He appears in the chapter "The Rabbit Sends a Little Bill".
Role in the book
In the book when Alice shrinks to a tiny size, and escapes into the White Rabbit's garden, she finds the Puppy (now apparently enormous to her, but actually a normal sized dog) and briefly plays with him, and compares it to "a game of play with a cart-horse, and expecting every moment to be trampled under his feet". At the conclusion of the game, she leaves him, with a slight regret of the necessity to do so. In the book when
Tim Burton version
In the 2010 film, the Puppy has become a bloodhound named Bayard: voiced by Timothy Spall and forced to hunt for Alice by the Knave of Hearts. Bayard tracks Alice to the tea party held by the Mad Hatter, March Hare, and Dormouse, where the Hatter hides her in a teapot and tells Bayard to lead the knights away, which he does. Some time afterwards, he finds Alice again under the Mad Hatter's hat, and takes her to the Red Queen's castle by Alice's own request, where she arranges to rescue the Mad Hatter from the Queen's captivity. After her failure there, Bayard leads Alice to the White Queen's castle, while she rides the Bandersnatch.
Prader–Willi syndrome
Prader–Willi syndrome (/ˈprɑːdər ˈvɪli/; abbreviated PWS) is a rare genetic disorder in which seven genes (or some subset thereof) on chromosome 15 (q 11–13) are deleted or unexpressed (chromosome 15q partial deletion) on the paternal chromosome. It was first described in 1956 by Andrea Prader (1919–2001), Heinrich Willi (1900–1971), Alexis Labhart (1916–1994), Andrew Ziegler, and Guido Fanconi of Switzerland. Characteristic of PWS is "low muscle tone, short stature, incomplete sexual development, cognitive disabilities, behavior problems, and a chronic feeling of hunger that can lead to excessive eating and life-threatening obesity." The incidence of PWS is between 1 in 25,000 and 1 in 10,000 live births.
The paternal origin of the genetic material that is affected in the syndrome is important because the particular region of chromosome 15 involved is subject to parent-of-origin imprinting, meaning that for a number of genes in this region, only one copy of the gene is expressed while the other is silenced through imprinting. For the genes affected in PWS, it is the maternal copy that is usually imprinted (and thus is silenced), while the mutated paternal copy is not functional. This means that while most people have one working and one silenced set of these genes, people with PWS have a non-working set and a silenced set. If the maternally derived genetic material from the same region is affected instead, the sister Angelman Syndrome is the result.
