PON

PON or Pon may refer to:

Business

Technology

Medicine/Chemistry

Religion

Fiction

Other

PON1

Serum paraoxonase/arylesterase 1 (PON1) also known as A esterase , homocysteine thiolactonase or serum aryldialkylphosphatase 1 is an enzyme that in humans is encoded by the PON1 gene. Paraoxonase 1 has esterase and more specifically paraoxonase activity. Serum PON1 is found in all mammalian species studied so far but is not present in the serum of birds, fish and reptiles or in insects. PON1 is the first discovered member of a multigene family also containing PON2 and PON3, the genes for which are located adjacent to each other on chromosome 7.

Structure

Human PON1 is a glycoprotein composed of 354 amino acids and has a molecular weight of 43000 Daltons which associates with high-density lipoprotein (HDL, "good cholesterol") in the circulation. Serum PON1 is secreted mainly by the liver although local synthesis occurs in several tissues and PON1 protein is found in almost all tissues. X-ray crystallography has revealed the structure of PON1 to be a 6 bladed propeller with a unique lid structure covering the active site passage and which allows association with HDL. The structure contains 2 calcium ions which are essential for catalytic activity and enzyme stability.

Changé

Changé may refer to the following places in France:

See also

Changüí

Changüí is a style of Cuban music which originated in the early 19th century in the eastern region of Guantánamo Province, specifically Baracoa. It arose in the sugar cane refineries and in the rural communities populated by slaves. Changüí combines the structure and elements of Spain's canción and the Spanish guitar with African rhythms and percussion instruments of Bantu origin. Changüí is considered a predecessor of son montuno (the ancestor of modern salsa), which has enjoyed tremendous popularity in Cuba throughout the 20th century.

Many people confuse changüi with other styles, but academically you are playing changüí is once the ensemble consists of these 4 musical instruments: marímbula, bongo, tres, güiro (or guayo) and a singer(s). So it isn't really the patterns syncopation, but rather the ensemble style.

Changüí is related to the other regional genres of nengón and kiribá. It actually is a descendant of nengón. The changüi ensemble consists of: marímbula, bongos, tres ("Cubanized" guitar), güiro (or guayo) and one or more singers. Changüi does not use the Cuban key pattern (or guide pattern) known as clave. The tres typically plays offbeat guajeos (ostinatos), while the guayo plays on the beat.

Fur Fighters

Fur Fighters is a video game developed by Bizarre Creations and published by Acclaim for the Dreamcast in 2000, then later for Microsoft Windows. The game was designed very much as a standard third-person shooter, but used a world populated by cute little animals as its setting. As a result, the game's depiction of violence is very cartoon-like without losing any of its intensity. In 2001, an updated version for the PlayStation 2 was released as Fur Fighters: Viggo's Revenge. On July 20, 2012, members of Muffin Games, ex-Bizarre Creations staff, announced a conversion for iPad, called Fur Fighters: Viggo on Glass.

Gameplay