PHF1

PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene.

This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.

References

Further reading

External links

  • PHF1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)


    • This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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    by: They Might Be Giants

    Underneath a big clock
    At the corner of 5th Avenue and 22nd Street
    I stood and waited for a girl I knew
    At the spot where we agreed to meet
    It was four minutes of two
    At four of two, I stood waiting for the girl
    I was four minutes early for the date we had planned
    I was planning to say I was in love with her
    Just as soon as she showed for a two o'clock date
    And the clock said four of two
    At four of two, I was staring into space
    She was not yet late, according to the clock
    I was feeling nervous so I kept looking up
    At the clock sticking out of the side of the building
    And it still said four of two
    At four of two, I began to feel tired
    And I rubbed my eyes, and again I checked the time
    It seemed as if the sky was growing dark
    But I felt reassured when I looked at the clock
    And it still said four of two
    I lay my head down on the sidewalk
    So in case she were coming I would have a better view
    But no one was there so I stretched out
    And closed my eyes for a second or two
    It was four minutes of two
    At once I awoke to a futuristic world
    There were flying cars and gigantic metal bugs
    I'd grown a beard, it was long and white
    But I knew that the girl would be coming very soon
    For though everything had changed, there was still that clock




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