Perfluorobutane (PFB) is a colorless gas. It is a simple fluorocarbon with a n-butane skeleton and all the hydrogen atoms replaced with fluorine atoms. It is used as a replacement for Halon 1301fire extinguishers, as well as the gas component for newer generation microbubbleultrasound contrast agents. Sonazoid is one such microbubble formulation developed by Amersham Health that uses perfluorobutane for the gas core.