Gwar

Gwar, often styled as GWAR, is an American heavy metal band formed in Richmond, Virginia, United States, in 1984, composed of and operated by a frequently rotating line-up of musicians, artists and filmmakers collectively known as Slave Pit Inc.

Easily identified by their distinctively grotesque costumes, Gwar's core thematic and visual concept revolves around an elaborate science fiction-themed mythology which portrays the band members as barbaric interplanetary warriors, a narrative which serves as the basis for all of the band's albums, videos, live shows and other media. Rife with over-the-top violent, sexual, and scatological humour typically incorporating social and political satire, Gwar have attracted both acclaim and controversy for their music and stage shows, the latter of which notoriously showcase enactments of graphic violence that result in the audience being sprayed with copious amounts of fake blood. Such stagecraft regularly leads Gwar to be labeled a "shock rock" band by the media.

Drip

Drip may refer to:

Entertainment

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DRIP

DRIP may refer to:

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MED1

Mediator of RNA polymerase II transcription subunit 1 also known as DRIP205 or Trap220 is a subunit of the Mediator complex and is a protein that in humans is encoded by the MED1 gene. MED1 functions as a nuclear receptor coactivator.

Function

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The mediator of RNA polymerase II transcription subunit 1 protein is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes [e.g., thyroid hormone receptor-(TR-) associated proteins that interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors]. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.