Pellagra

Pellagra is a vitamin deficiency disease most frequently caused by a chronic lack of niacin (vitamin B3 or synonym: vitamin PP (from: Pellagra Preventing factor)) in the diet. It can be caused by decreased intake of niacin or tryptophan, and possibly by excessive intake of leucine. It may also result from alterations in protein metabolism in disorders such as carcinoid syndrome or Hartnup disease. A deficiency of the amino acid lysine can lead to a deficiency of niacin, as well.

Signs and symptoms

Pellagra is classically described by "the three Ds": diarrhea, dermatitis, dementia. A more comprehensive list of symptoms includes:

  • High sensitivity to sunlight
  • Aggression
  • Dermatitis, alopecia (hair loss), edema (swelling)
  • Smooth, beefy red glossitis (tongue inflammation)
  • Red skin lesions
  • Insomnia
  • Weakness
  • Mental confusion
  • Ataxia (lack of coordination), paralysis of extremities, peripheral neuritis (nerve damage)
  • Diarrhea
  • Dilated cardiomyopathy (enlarged, weakened heart)
  • Eventually dementia
    • Loading... please wait...
    This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Pellagra

    Podcasts:

    Email this Page Play all in Full Screen Show More Related Videos
    PLAYLIST TIME:

    Fraught

    by: Be'lakor

    Searching, the abstract colours reason
    But I persist to fail in the absence of faith
    Cycles bound by throes of attrition
    Oft united, yet surely more is lost in time
    Beyond fathom, billions firing
    Flashes burn and spew prostrate
    Wisped monads from crimson puncture
    Our bonds are broken, all meaning sundered
    Striving for constant reduction
    Bursting from the pit beneath
    Unyielding yet beyond the grasp
    Of scale and form
    Nothingness born
    Fleetingly
    Of sprawl and flame
    From nothing it came
    Seemingly
    The gap between us tears apart
    Impel our end
    Layers surge and strip away
    Cast into nought
    Of matter torn
    As eons I mourn
    Achingly
    Of atoms maimed
    As epochs are tamed
    Blindingly
    In that final absence,




    ×
    ×
    ×
    ×