Paroxetine
Paroxetine, also known by the trade names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, social anxiety disorder, panic disorder, posttraumatic stress disorder, generalized anxiety disorder and premenstrual dysphoric disorder. It has also been used in the treatment of hot flashes and night sweats associated with menopause.
It has a similar tolerability profile to other SSRIs. The common side effects include drowsiness, dry mouth, loss of appetite, sweating, trouble sleeping and delayed ejaculation. It may also be associated with a slightly increased risk of birth defects. The incidence of withdrawal symptoms is higher with paroxetine and venlafaxine. Several studies have associated paroxetine with suicidal thinking and behavior in children and adolescents.
Marketing of the drug began in 1992 by the pharmaceutical company SmithKline Beecham, known since 2000 as GlaxoSmithKline. Generic formulations have been available since 2003 when the patent expired. The United States Department of Justice fined GlaxoSmithKline $3 billion in 2012, including a sum for withholding data on paroxetine, unlawfully promoting it for under-18s, and preparing an article, following one of its clinical trials, study 329, that misleadingly reported the drug was effective in treating adolescent depression.
Podcasts:
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by Zebrahead
Brixton
by: ZebraheadStarted off as I fall in a ball of flame
Burning out on your sentiment, it's all in vain
Shot your 44 caliber words with aim
You might've killed the heart but you left the brain
Devastated and I hate it, see your eyes are insane
Gray and dissipated building just like rust on a chain drained
Dislocated echo in the things you say
You might've killed the heart but you left the brain
Your words are making me sick
No more lies, enough with your rhetoric
Whoa, what you got to hide?
Whoa, you're dead inside
What a wonderful lie
Don't you feel alive?
Whoa, what you got to hide?
Whoa, you're dead inside
What a wonderful lie
Don't you feel alive?
Cut away, cut it all away now
Cut away, cut it all away now
Cut away, cut it all away now
Cut me off at the pass, as a hydroplane
Crashing down from your promises, all were fake
Shot your 44 caliber words with aim
You might've killed the heart but you left the brain
Formulated and I'm fated to withstand the pain
Wave of generated conscience from the edge of a blade
Feigned, fabricated echo in the things you say
You might have killed the heart but you left the brain
Your words are making me sick
No more lies, enough with your rhetoric
Whoa, what you got to hide?
Whoa, you're dead inside
What a wonderful lie
Don't you feel alive?
Whoa, what you got to hide?
Whoa, you're dead inside
What a wonderful lie
Don't you feel alive?
Switch all the lights off, tell me what you want from me
Take my time and my energy
Turning you heart off came about so easily
It's not enough but it's plenty
Bleed in the black out, said that you'd be there for me
Now you're gone and we're history
Screaming your lungs out, say you want what's best for me
Give it up, you abandoned me
Whoa, what you got to hide?
Whoa, you're dead inside
What a wonderful lie
Don't you feel alive?
Whoa, what you got to hide?
Whoa, you're dead inside
What a wonderful lie
Don't you feel alive?
Cut away, cut it all away now
Cut away, cut it all away now