PARD6B

Partitioning defective 6 homolog beta is a protein that in humans is encoded by the PARD6B gene.

Function

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.

Interactions

PARD6B has been shown to interact with:

  • CDC42,
  • Protein kinase Mζ,
  • RAC1, and
  • RHOQ.
  • References

    Further reading


    Podcasts:

    PLAYLIST TIME:
    ×