Pain

Pain is a distressing feeling often caused by intense or damaging stimuli, such as stubbing a toe, burning a finger, putting alcohol on a cut, and bumping the "funny bone". Because it is a complex, subjective phenomenon, defining pain has been a challenge. The International Association for the Study of Pain's widely used definition states: "Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage." In medical diagnosis, pain is a symptom.

Pain motivates the individual to withdraw from damaging situations, to protect a damaged body part while it heals, and to avoid similar experiences in the future. Most pain resolves once the noxious stimulus is removed and the body has healed, but it may persist despite removal of the stimulus and apparent healing of the body. Sometimes pain arises in the absence of any detectable stimulus, damage or disease. Simple pain medications are useful in 20% to 70% of cases.

Pain (philosophy)

Philosophy of pain may be about suffering in general or more specifically about physical pain. The experience of pain is, due to its seeming universality, a very good portal through which to view various aspects of human life. Discussions in philosophy of mind concerning qualia has given rise to a body of knowledge called philosophy of pain, which is about pain in the narrow sense of physical pain, and which must be distinguished from philosophical works concerning pain in the broad sense of suffering. This article covers both topics.

Historical views of pain

Two near contemporaries in the 18th and 19th centuries, Jeremy Bentham and the Marquis de Sade had very different views on these matters. Bentham saw pain and pleasure as objective phenomena, and defined utilitarianism on that principle. However the Marquis de Sade offered a wholly different view - which is that pain itself has an ethics, and that pursuit of pain, or imposing it, may be as useful and just as pleasurable, and that this indeed is the purpose of the state - to indulge the desire to inflict pain in revenge, for instance, via the law (in his time most punishment was in fact the dealing out of pain). The 19th-century view in Europe was that Bentham's view had to be promoted, de Sade's (which it found painful) suppressed so intensely that it - as de Sade predicted - became a pleasure in itself to indulge. The Victorian culture is often cited as the best example of this hypocrisy.

Pain (Puff Daddy song)

"Pain" is a song on Puff Daddy's 1997 album No Way Out.

The song is about tragedies from Puff Daddy's life, including the murder of his father Melvin Combs in 1972, the New York City College Stampede of 1991 and the death of his label-mate and friend Notorious BIG in 1997.

The song features audio from Notorious BIG which was recorded before his death when the song was made.

There is a completely different song also entitled Pain on the follow-up album Forever.



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Latest News for: pain neuropathic

MIRA Pharmaceuticals Enrolls First Subjects in Phase 1 Clinical Trial of Ketamir-2 for Neuropathic Pain

ACCESSWIRE 01 Apr 2025
This important clinical milestone follows compelling preclinical data, where Ketamir-2 demonstrated superior efficacy compared to FDA-approved neuropathic pain treatments, including pregabalin and gabapentin.

OKYO Pharma Announces Positive Data in Long-Term Stability of Urcosimod

Pharmiweb 31 Mar 2025
Neuropathic corneal pain is a condition that causes severe pain and sensitivity of the eyes, face, or head ... OKYO is focused on the discovery and development of novel molecules to treat neuropathic corneal pain and dry eye disease.

Dogwood Therapeutics Announces Fourth Quarter and Full Year 2024 Financial Results

Hastings Tribune 31 Mar 2025
-Dogwood Therapeutics, Inc. commenced dosing of patients in the Halneuron® Chemotherapy Induced Neuropathic Pain (“CINP”) Phase 2b Trial - ... .

Tips for dealing with spider bites in the South

Savannah Morning News 28 Mar 2025
The bite is neuropathic like the black widow, but it generally does not spread, so it’s painful but not life threatening.Southern House Spider ... They may cause minor localized pain, redness, and ...

Diabetic foot pain: Expert tips on how to cope

The Cincinnati Herald 26 Mar 2025
This type of pain, resulting from damage to sensory nerve fibres, is called neuropathic pain. As scientists in the field of pain and pain management we work on neuropathic pain in people living with diabetes and its management.

AI-driven device by PGI set to transform neuropathic pain diagnosis in India

The Times of India 23 Mar 2025
PGI's medical innovation, conceived and developed entirely in India, is set to redefine neuropathic pain management, providing a lifeline to millions suffering from conditions like diabetic neuropathy and sciatica.

Researchers search for more precise ways to measure pain

Detroit news 23 Mar 2025
... lupus (an example of inflammatory pain) and carpal tunnel syndrome (an example of neuropathic pain, which arises from damage or dysfunction of the nervous system, rather than from damage to tissue).

What is Alan Jackson's health condition? Everything you should know about Charcot-Marie-Tooth disease

The Times of India 21 Mar 2025
The treatment program often includes physiotherapy, occupational therapy, orthoses, and walking aids, NSAIDs for pain control, antidepressants for neuropathic pain, surgeries like osteotomy in case of deformities.

Doctor reveals how to relieve debilitating pelvic pain of common condition affecting millions of women ...

The Daily Mail 19 Mar 2025
The chronic pain of endometriosis stems from the tissue growing outside of the uterus, which breaks down with each menstrual cycle ... ‘In cases where pain has a neuropathic component, nerve pain medications can also be effective.’.

Pain medications are less effective in women than men, here’s why

The Times of India 18 Mar 2025
“This study identifies a very unique type of biological process through a specific immune cell that is distinctive to each sex.”The study focused on neuropathic pain, which occurs due to an injury of the nerve or nervous system.

Georgia has 5 common venomous spiders. Here's what to watch for, how to care for bites

Savannah Morning News 18 Mar 2025
The bite is neuropathic like the black widow, but it generally does not spread, so it’s painful but not life threatening.Southern House Spider ... They may cause minor localized pain, redness, and swelling, but these symptoms usually resolve quickly.

CS Diagnostics (OTCQB: CSDX) CS-Protect Hydrogel FDA Approval on Fasttrack – GNPX, BON, SES, BETRF ...

GetNews 18 Mar 2025
CS Diagnostics (OTCQB ... has been granted a composition of matter patent (US2023/0219955) for BETR-001, a non-hallucinogenic LSD derivative in development for major depressive disorder, anxiety, and neuropathic pain, extending protection until 2042 ... ....

Best Delta 9 Gummies: 5 THC Edibles To Buy Online in 2024

The Daily Democrat 17 Mar 2025
Joy Organics – Strongest Delta 9 Gummies For Pain ... Studies have shown that THC can significantly reduce chronic pain in various conditions, including neuropathic pain and pain associated with multiple sclerosis, arthritis, and fibromyalgia.

MIRA Pharmaceuticals Expands Ketamir-2 Development with Topical Treatment for Localized Neuropathic and Inflammatory Pain

ACCESSWIRE 13 Mar 2025
This advancement expands the Company's pain management portfolio beyond its ongoing Ketamir-2 oral treatment for neuropathic pain, offering a novel, targeted approach for localized pain relief.

Spinal TRPC3 promotes neuropathic pain and coordinates phospholipase C–induced mechanical hypersensitivity

PNAS 13 Mar 2025
... suppressed pain hypersensitivity in a neuropathic pain mouse model.
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