PSS may refer to:

Science [link]

• Packet Switch Stream, a British packet-switched network
• Patterned Sapphire Substrate
• Perceived Stress Scale, a psychological instrument for measuring perceived stress in humans
• Physica Status Solidi, the family of academic journals focused on solid state physics, published by Wiley-VCH
• Physical symbol system, Hypothesis concerning cognition. Closely connected to AI-research
• Physiologic saline solution
• Photostationary state, the equilibrium chemical composition under a specific kind of electromagnetic irradiation
• Plasma sound source, a means of making sonar underwater
• Polystyrene Sulfonic Acid, also known as Sodium polystyrene sulfonate or poly(styrenesulfonate)
• Portosystemic shunt, a disease found in humans, cats and dogs
• Practical Salinity Scale, the conductivity ratio of a sea water sample to a standard KCl solution
• Progressive systemic sclerosis, a rare chronic disease
• Probabilistic Signature Scheme, a secure way of creating signatures with RSA (see also: PKCS1#Schemes)

Software development [link]

• Personal Software Services, a defunct computer software developer

Other [link]

• Psalms, a book of the Hebrew Bible
• Passenger service system, systems used by airlines to manage reservations, inventory and check-in
• Product Support Services, a Microsoft business unit
• Radio-controlled glider#PSS for Power Scale Soaring, A form of radio controlled model flying
• Paikiasothy Saravanamuttu Stadium, a sporting stadium in Colombo, Sri Lanka
• Product service system, a system of consumer access to products, as an alternative to personal product ownership
• PSS Silent Pistol, a Soviet-designed silent handgun
• Pinetree Secondary School, a high school in School District 43 Coquitlam
• PSS Sleman for Persatuan Sepakbola Sleman, an Indonesian football club
• PlayStation Store, online market on the Sony PlayStation Network
• PSS-SOF, Precision Strike Suite Special Operations Forces
• PSS, Protective Security Specialist (US Department of State, Bureau of Diplomatic Security Job Title/Qualification)

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