PSG1 (gene)

Pregnancy specific beta-1-glycoprotein 1 (PSBG-1) also known as CD66f (Cluster of Differentiation 66f), is a protein that in humans is encoded by the PSG1 gene. Pregnancy-specific glycoproteins (PSGs) are a complex consisting of carbohydrate and protein, which is present in the mammalian body specifically during pregnancy. This glycoprotein is the most abundant protein found in the maternal bloodstream during the later stages of pregnancy and it is of vital importance in fetal development. The PSG functions primarily as an immunomodulator to protect the growing fetus.

Structure

PSG is a member of the immunoglobulin (Ig) superfamily and contains four immunoglobulin domains.

Gene

A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.

Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term "having a gene" (e.g., "good genes," "hair colour gene") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.

Eugene (given name)

Eugene is a common (masculine) first name that comes from the Greek εὐγενής (eugenēs), "noble", literally "well-born", from εὖ (eu), "well" and γένος (genos), "race, stock, kin".Gene is a common shortened form. The feminine variant is Eugenia or Eugénie.

Male foreign-language variants include:

Notable people

Christianity

  • Pope Eugene I, pope from 655 to 657
  • Pope Eugene II, pope from 824 to 827
  • Pope Eugene III, pope from 1145 to 1153
  • Pope Eugene IV, pope from 1431 to 1447
  • Charles-Joseph-Eugene de Mazenod (1782–1861), the founder of the Missionary Oblates of Mary Immaculate
  • St. Eugene, one of the deacons of Saint Zenobius
  • Saint Eugenios of Trebizond was the patron saint of the Empire of Trebizond
  • Pope Pius XII, pope from 1939 to 1958, given name Eugenio Maria Giuseppe Giovanni Pacelli
  • Eugene Antonio Marino (1934–2000), first African-American archbishop in the United States
  • Eugênio de Araújo Sales (1920–2012), Roman Catholic cardinal from Brazil
  • Military

  • Eugène de Beauharnais (1781–1824), the stepson and adopted child of Napoleon
  • Gene (novel)

    Gene is a thriller novel by Stel Pavlou (born 1970), published in 2005 in England by Simon & Schuster. It is published in several languages with some title changes. The Italian edition has the title La Conspirazione del Minotauro (The Minotaur Conspiracy). The novel is about a fictional New York detective, James North, who in the process of hunting down a criminal, uncovers a genetics experiment to unlock past lives through genetic memory, therefore achieving a kind of immortality. In so doing North discovers his own origins, that of a soldier from the Trojan War who is reincarnated seven times through history, forced to confront his nemesis each time, all for the loss of his one true love.

    Characters

    Cyclades (born circa 1300 BC)

    Incarnations of Cyclades

  • Detective James North (2004 AD)
  • Eugene Dybbuk (2004 AD)
  • Aquilo (75 AD)
  • Aisha (2004)
  • William Porter (2004)
  • Athanatos (born circa 1500 BC)

    Incarnations of Athanatos

  • Detective James North (2004 AD)
  • Eugene Dybbuk (2004 AD)
  • Savage (2004 AD)
  • Heckler & Koch PSG1

    The PSG1 (Präzisionsschützengewehr, German for "precision shooting rifle") is a semi-automatic sniper rifle designed by the German company Heckler & Koch of Oberndorf am Neckar.

    Development

    This rifle is said to have been developed in response to the Munich massacre at the 1972 Summer Olympics. The West German police units could not engage the terrorists quickly enough to prevent them from killing their hostages. H&K was then commissioned to create a high accuracy, large magazine capacity, semi-automatic rifle for police and military use.

    In addition, the rifle has been licensed for local production in Pakistan by Pakistan Ordnance Factories (POF) as the PSR-90 and Mexico by SEDENA as the Morelos Bicentenario.

    Design details

    The PSG1 is mechanically based on the G3 rifle and features a low-noise bolt closing device (similar to the forward assist on many M16 rifles). Its shot-to-shot variation is expected to be better than 1 minute of angle (MOA) with match ammunition. This level of accuracy is only average compared to most modern sniper rifles, but is still exceptional for a semi-automatic rifle and at one time was claimed to be "one of the most accurate semi-automatic sniper rifles in the world."

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