PRKCH
Protein kinase C eta type is an enzyme that in humans is encoded by the PRKCH gene.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
Podcasts:
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by Kittie
Brackish
by: KittieShe is not scared to die..
The best things in life drive her to cry.
Crucify then learn..
(take so much away from inside you, makes no sence,
you know he can't guide you, he's no fucking shoulder to lean on, be strong!)
Sit and watch me burn..
She's led to believe, that it be ok,
look at your face, scarred in dismay,
but times have changed, and so have you..
I think I'd rather crucify then learn
(take so much away from inside you, makes no sence,
you know he can't guide you, he's no fucking shoulder to lean on, be strong!)
Sit and watch me burn..
I'd like to take you down, and show you
deep inside, my life my inner workin
so smell and lack of inner pride,
to touch upon the surface, is not for
what it seems, I take away
my problems, but only in my dreams.
(take so much away from inside you, makes no sence,
you know he can't guide you, he's no fucking shoulder to lean on, be strong!)
Crucify the learn..
(take so much away from inside you, makes no sence,
you know he can't guide you, he's no fucking shoulder to lean on, be strong!)
Crucify then learn..