PKP3

Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene.

Function

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.

Interactions

PKP3 has been shown to interact with:

References

Further reading