PGI

PGI may refer to:

Prostacyclin

Prostacyclin (also called prostaglandin I2 or PGI₂) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator.

As a drug, it is also known as "epoprostenol". The terms are sometimes used interchangeably.

History

During the 1960s, a U.K. research team, headed by Professor John Vane, began to explore the role of prostaglandins in anaphylaxis and respiratory diseases. Working with a team from the Royal College of Surgeons, Sir John discovered that aspirin and other oral anti-inflammatory drugs work by inhibiting the synthesis of prostaglandins. This critical finding opened the door to a broader understanding of the role of prostaglandins in the body.

Sir John and a team from the Wellcome Foundation, had identified a lipid mediator they called “PG-X,” which inhibits platelet aggregation. PG-X, which later would become known as prostacyclin, is 30 times more potent than any other then-known anti-aggregatory agent.

PGi

PGi, or Premiere Global Services, Inc., is a multinational corporation and global provider of conferencing and collaboration solutions. Its products include audio conferencing, web conferencing, webcasting, videoconferencing and virtual meeting solutions such as iMeet and GlobalMeet. PGi provides global SaaS (software as a service) and cloud computing solutions to small, medium and enterprise businesses.

History

Premiere Technologies, Inc. was founded by Boland T. Jones in 1991. In February 2000, the company name was officially changed from Premiere Technologies to Ptek Holdings, Inc. (NASDAQ: PTEK) and in January 2005, the name was again changed to Premiere Global Services, Inc. The company’s stock is traded on the New York Stock Exchange under the symbol “PGI” and is included in the Russell 2000 Index.

The company's corporate headquarters is located in Atlanta, Georgia, and PGi employs over 2,100 people in 25 offices around the world, including London, Tokyo, Sydney, Hong Kong, Paris, Auckland, Frankfurt, Toronto, New York, Chicago, Clonakilty, Pasadena, and Austin, Texas with an annual revenue of $526.9M USD as of 2013.