| Cyclin-dependent kinase 14 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | CDK14; PFTAIRE1; PFTK1 | ||||||||||||
| External IDs | OMIM: 610679 MGI: 894318 HomoloGene: 7888 ChEMBL: 6162 GeneCards: CDK14 Gene | ||||||||||||
| EC number | 2.7.11.22 | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 5218 | 18647 | |||||||||||
| Ensembl | ENSG00000058091 | ENSMUSG00000028926 | |||||||||||
| UniProt | O94921 | O35495 | |||||||||||
| RefSeq (mRNA) | NM_012395.2 | NM_011074.2 | |||||||||||
| RefSeq (protein) | NP_036527.1 | NP_035204.2 | |||||||||||
| Location (UCSC) | Chr 7: 90.1 – 90.84 Mb |
Chr 5: 4.8 – 5.42 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Serine/threonine-protein kinase PFTAIRE-1 is an enzyme that in humans is encoded by the PFTK1 gene.[1][2][3]
Interactions [link]
PFTK1 has been shown to interact with SEPT8.[4]
References [link]
- ^ Lazzaro MA, Albert PR, Julien JP (Jul 1997). "A novel cdc2-related protein kinase expressed in the nervous system". J Neurochem 69 (1): 348–64. DOI:10.1046/j.1471-4159.1997.69010348.x. PMID 9202329.
- ^ Yang T, Chen JY (Apr 2001). "Identification and cellular localization of human PFTAIRE1". Gene 267 (2): 165–72. DOI:10.1016/S0378-1119(01)00391-2. PMID 11313143.
- ^ "Entrez Gene: PFTK1 PFTAIRE protein kinase 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5218.
- ^ Yang, Tao; Gao Yan-Kun, Chen Jiang-Ye (Jul. 2002). "KIAA0202, a human septin family member, interacting with hPFTAIRE1". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (China) 34 (4): 520–5. ISSN 0582-9879. PMID 12098780.
Further reading [link]
- Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (6): 355–64. DOI:10.1093/dnares/5.6.355. PMID 10048485.
- Yang T, Gao YK, Chen JY (2002). "KIAA0202, a human septin family member, interacting with hPFTAIRE1.". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 34 (4): 520–5. PMID 12098780.
- Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. DOI:10.1126/science.1083423. PMC 2882961. PMID 12690205. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2882961.
- Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. DOI:10.1038/nature01782. PMID 12853948.
- Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. DOI:10.1126/science.1105776. PMID 15761153.
- Gao Y, Jiang M, Yang T, et al. (2006). "A Cdc2-related protein kinase hPFTAIRE1 from human brain interacting with 14-3-3 proteins.". Cell Res. 16 (6): 539–47. DOI:10.1038/sj.cr.7310071. PMID 16775625.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. DOI:10.1038/msb4100134. PMC 1847948. PMID 17353931. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948.
- Shu F, Lv S, Qin Y, et al. (2007). "Functional characterization of human PFTK1 as a cyclin-dependent kinase.". Proc. Natl. Acad. Sci. U.S.A. 104 (22): 9248–53. DOI:10.1073/pnas.0703327104. PMC 1890480. PMID 17517622. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1890480.
- Denoeud F, Kapranov P, Ucla C, et al. (2007). "Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.". Genome Res. 17 (6): 746–59. DOI:10.1101/gr.5660607. PMC 1891335. PMID 17567994. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1891335.
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