Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
Why don't you hang these steps upside down,
We'll walk backwards and feel the blood drain to our heads
While your creeping away why don't we pull the punches back?
And perhaps rebuild those severed ties;
When I felt you destroyed everything I knew
I felt ever so slowly becoming you.
Where has my heart gone, and where has my faith gone?
And why am I still here, hating every breath you take
Where has my heart gone, and where has my faith gone?
And why am I still here, hating every breath you take
Every step you take, and every move you make?
And just wishing that you'd take your fucking last breath toward expiration;
I can't even make myself out in the fog,
You are the swamp,
You are the sand beneath my feet pulling me down.
I have no face for your name, your roots never went any further down;
I felt them writhe in the cellars of my mind,
Rotted through right where they fell, yet here I am.
The wasted pulp of what you are.
Where has my heart gone, and where has my faith gone?
And why am I still here, hating every breath you take
Every step you take, and every move you make?
And just wishing that you'd take your fucking last breath toward expiration;
But at least if I fall
I can say we failed (we failed) together (together)
Sure to be the only thing we ever shared
'cause you were never there (never there)
And I'm yet to feel like I'm even here.
If I sink into the swamp that is misery,