P2RY8

P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.

Function

The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.

Clinical relevance

Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma.

See also

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.