P. C. Sreeram

P. C. Sreeram (born 26 January 1956) is an Indian cinematographer and film director who works mainly in the Tamil film industry. A student of Madras Film Institute, Sreeram is widely regarded as the "Guru of Cinematography" (English: (lit.) The mentor of cinematography). Apart from his cinematographic works, he was much appreciated for his directorial venture Kuruthipunal which was submitted by India as its official entry to the Oscars in 1996. Sreeram is well known for his association with Mani Ratnam and received critical acclaim for his work in films such as Mouna Ragam, Nayagan, Agni Natchathiram and Geetanjali. He has worked as a cinematographer in over 30 films spanning across Tamil, Telugu, Malayalam, Kannada and Hindi, besides directing three films and a few TV commercials.

Early life and family

Sreeram was born on 26 January 1956 in Madras, (now Chennai, Tamil Nadu). He was the third child in the family and has two sisters. Sreeram's aspiration towards films grew much during his childhood days. He was educated at the Vidya Mandir Senior Secondary School, Mylapore, Chennai. As a student he was not interested in studies and only managed to pass the exams. He developed an early interest in photography and years after struggle he joined the Madras Film Institute to do a course in cinematography. PC Sreeram in his teens when he was a student in the film institute had a long association with the budding creators of his generation. Together with his friends Kamal Hassan, C. Rudhraiya, Santhana Bharathi, Radharavi, R. C. Sakthi and few others they were called sanmac group where they used to join together at a hotel in Chennai and share their learnings about cinema and future dreams of making a perfect cinema.

PC

PC or pc may refer to:

Computing

Science

Chemistry

Medicine

Physics

Psychology

Modular connector

A modular connector is an electrical connector that was originally designed for use in telephone wiring, but has since been used for many other purposes. Many applications that originally used a bulkier, more expensive connector have converted to modular connectors. Probably the most well known applications of modular connectors are for telephone jacks and for Ethernet jacks, both of which are nearly always modular connectors.

Modular connectors were originally used in the Registration Interface system, mandated by the Federal Communications Commission (FCC) in 1976 in which they became known as registered jacks. The registered jack specifications define the wiring patterns of the jacks, not the physical dimensions or geometry of the connectors of either gender. Instead, these latter aspects are covered by ISO standard 8877, first used in ISDN systems. TIA/EIA-568 is a standard for data circuits wired on modular connectors.

Other systems exist for assigning signals to modular connectors; physical interchangeability of plugs and jacks does not ensure interoperation, nor protection from electrical damage to circuits. For example, modular cables and connectors have been used to supply low-voltage AC or DC power and no clear standard exists for this application.

P&C

P&C may refer to:

P5 (microarchitecture)

The first Pentium microprocessor was introduced by Intel on March 22, 1993. Dubbed P5, its microarchitecture was the fifth generation for Intel, and the first superscalar IA-32 microarchitecture. As a direct extension of the 80486 architecture, it included dual integer pipelines, a faster floating-point unit, wider data bus, separate code and data caches and features for further reduced address calculation latency. In 1996, the Pentium with MMX Technology (often simply referred to as Pentium MMX) was introduced with the same basic microarchitecture complemented with an MMX instruction set, larger caches, and some other enhancements.

The P5 Pentium competitors included the Motorola 68060 and the PowerPC 601 as well as the SPARC, MIPS, and Alpha microprocessor families, most of which also used a superscalar in-order dual instruction pipeline configuration at some time.

Intel's Larrabee multicore architecture project uses a processor core derived from a P5 core (P54C), augmented by multithreading, 64-bit instructions, and a 16-wide vector processing unit. Intel's low-powered Bonnell microarchitecture employed in Atom processor cores also uses an in-order dual pipeline similar to P5.

1-Pyrroline-5-carboxylic acid

1-Pyrroline-5-carboxylic acid, also known as 1-pyrroline-5-carboxylate, delta-1-pyrroline-5-carboxylic acid, and P5C, is an imino acid. The stereoisomer (S)-1-pyrroline-5-carboxylate is a biosynthetic metabolite that is synthesized from proline by the enzyme pyrroline-5-carboxylate reductase and converted into the amino acid glutamate by the enzyme 1-pyrroline-5-carboxylate dehydrogenase.

Cytochrome P450, family 1, member A1

Cytochrome P450, family 1, subfamily A, polypeptide 1 is a protein that in humans is encoded by the CYP1A1 gene. The protein is a member of the cytochrome P450 superfamily of enzymes.

Function

CYP1A1 is involved in phase I xenobiotic and drug metabolism (one substrate of it is theophylline). It is inhibited by fluoroquinolones and macrolides and induced by aromatic hydrocarbons.

CYP1A1 is also known as AHH (aryl hydrocarbon hydroxylase). It is involved in the metabolic activation of aromatic hydrocarbons (polycyclic aromatic hydrocarbons, PAH), for example, benzo(a)pyrene (BP), by transforming it to an epoxide. In this reaction, the oxidation of benzo[a]pyrene is catalysed by CYP1A1 to form BP-7,8-epoxide, which can be further oxidized by epoxide hydrolase (EH) to form BP-7,8-dihydrodiol. Finally CYP1A1 catalyses this intermediate to form BP-7,8-dihydrodiol-9,10-epoxide, which is the ultimate carcinogen.

However, an in vivo experiment with gene-deficient mice has found that the hydroxylation of benzo(a)pyrene by CYP1A1 can have an overall protective effect on the DNA, rather than contributing to potentially carcinogenic DNA modifications. This effect is likely due to the fact that CYP1A1 is highly active in the intestinal mucosa, and thus inhibits infiltration of ingested benzo(a)pyrene carcinogen into the systemic circulation.