Drug overdose

The term drug overdose (or simply overdose or OD) describes the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced. An overdose may result in a toxic state or death.

Classification

The word "overdose" implies that there is a common safe dosage and usage for the drug; therefore, the term is commonly only applied to drugs, not poisons, though even poisons are harmless at a low enough dosage.

Drug overdoses are sometimes caused intentionally to commit suicide or as self-harm, but many drug overdoses are accidental, the result of intentional or unintentional misuse of medication. Intentional misuse leading to overdose can include using prescribed or unprescribed drugs in excessive quantities in an attempt to produce euphoria.

Usage of illicit drugs of unexpected purity, in large quantities, or after a period of drug abstinence can also induce overdose. Cocaine users who inject intravenously can easily overdose accidentally, as the margin between a pleasurable drug sensation and an overdose is small.

Let There Be Rock

Let There Be Rock is an album by Australian hard rock band AC/DC. It was the band's third internationally released studio album and the fourth to be released in Australia. All songs were written by Angus Young, Malcolm Young and Bon Scott. It was originally released on 21 March 1977 in Australia on the Albert Productions label. A modified international edition was released on 25 July 1977 on Atlantic Records.

Recording

By 1977, AC/DC had become extremely successful in their native Australia and had also achieved a degree of popularity in the U.K. and Europe, largely on the strength of their pulverizing live show. However, Atlantic Records in the United States had rejected the band's third album Dirty Deeds Done Dirt Cheap, feeling the production was not up to par, and the band, which had yet to tour America, returned to Albert Studios in Sydney to record another album. From the beginning, it appears they intended to make a statement, with guitarist Angus Young telling VH1's Behind the Music in 2000, "Me and Malcolm said, 'Well, we really want a lot of guitars,' you know? Big guitars." The band's first album released in Australia, High Voltage, had contained glam-rock elements, while their ensuing releases had been recorded piecemeal as the group toured incessantly and were also altered for international release. Let There Be Rock, on the other hand, was recorded in one go and represented a major evolution in the band's sound, with many critics and fans citing it as the first true AC/DC album; in his book Highway to Hell: The Life and Times of AC/DC Legend Bon Scott, author Clinton Walker observes, "Let There Be Rock was the first fully rounded AC/DC album. The band had finally found itself."

Overdose (Ciara song)

"Overdose" is a song recorded by American singer Ciara for her self-titled fifth studio album (2013). It was written by Josh Abraham, Oliver Goldstein, Ali Tamposi, Olivia Waithe and Ciara, while its production was handled by the former two. Ciara and Kuk Harrell were responsible for the song's vocal production. Notable for its shift from her more contemporary R&B sound towards a predominantly pop-orientated vocal style for the singer, "Overdose" served as a product of Ciara's experimentation and was recognized as the purest pop track on Ciara. An uptempo dance-pop, electropop and nu-disco song, its "club-friendly" production comprises rupturing synths and gritty, automatic beats. Its lyrical content act as an ode to codependency and are based on the subject of unhealthy infatuation.

"Overdose" initially leaked as an extended snippet on July 17, 2012, and then in full in June 2013. The song was originally recognized as a "fan favorite", before garnering favorable reviews from music critics, some of which went on to publish campaigns for the track be released as a single. Its accompanying artwork features Ciara's then-fiancé Future and resulted in widespread media attention for its provocative imagery. Though the song impacted urban contemporary and rhythmic contemporary radio in the United States—on September 18 and October 15, 2013, respectively—it failed to receive a full-scale single release, when its digital release was later cancelled and its accompanying music video and promotional performances failed to materialize. As a result, "Overdose" failed to enter the Billboard Hot 100 and garner success commercially.

Muscle

Muscle is a soft tissue found in most animals. Muscle cells contain protein filaments of actin and myosin that slide past one another, producing a contraction that changes both the length and the shape of the cell. Muscles function to produce force and motion. They are primarily responsible for maintaining and changing posture, locomotion, as well as movement of internal organs, such as the contraction of the heart and the movement of food through the digestive system via peristalsis.

Muscle tissues are derived from the mesodermal layer of embryonic germ cells in a process known as myogenesis. There are three types of muscle, skeletal or striated, cardiac, and smooth. Muscle action can be classified as being either voluntary or involuntary. Cardiac and smooth muscles contract without conscious thought and are termed involuntary, whereas the skeletal muscles contract upon command. Skeletal muscles in turn can be divided into fast and slow twitch fibers.

Muscles are predominantly powered by the oxidation of fats and carbohydrates, but anaerobic chemical reactions are also used, particularly by fast twitch fibers. These chemical reactions produce adenosine triphosphate (ATP) molecules that are used to power the movement of the myosin heads.

Muscle (TV series)

Muscle is an American television sitcom which aired on The WB from January 11, 1995 until May 24, 1995. It was set inside the fictional Survival Gym in New York City, and was a parody of prime time soap operas of the 1990s (with Fox's Melrose Place being the most noticeable inspiration). The series was created by Rob LaZebnik, and was executive produced by Paul Junger Witt, Tony Thomas and Gary S. Levine.

Muscle was one of the four sitcoms that aired as part of the original Wednesday night two-hour WB lineup, at 9:30/8:30c (with The Wayans Bros., The Parent 'Hood, and Unhappily Ever After being scheduled before it). It was the only one of the four that did not make it past the first season, and was also the first series to get canceled on the brand new WB. A clip can be found on YouTube under the name "muscle TV comedy". Like it's inspiration, ABC's Soap from the 1970s, it ended on a cliffhanger that was never resolved. Due to low ratings, there was no fan outrage as Soap had when it was cancelled.

Muscle (disambiguation)

A muscle is a contractile tissue in an animal's body used especially for movement.

Muscle or Muscles may also refer to:

Arts and entertainment

People

Other uses