The cardiac skeleton, also known as the fibrous skeleton of the heart, is a high density single structure of connective tissue that forms and anchors the valves and influences the forces exerted through them. The cardiac skeleton separates and partitions the atria (the smaller, upper two chambers) from the ventricles (the larger, lower two chambers). This is important because it forms the primary channel that electrical energy follows from the top to the bottom of the heart.
The cardiac skeleton consists of four bands of dense connective tissue, as collagen, that encircle the bases of the pulmonary trunk, aorta, and heart valves. While not a "true" skeleton, it does provide structure and support for the heart, as well as isolating the atria from the ventricles. In youth, this collagen structure is free of calcium adhesions and is quite flexible. With aging some calcium can accumulate on this skeleton. This accumulation contributes to the delay of the depolarisation wave in geriatric patients that can take place from the AV node and the bundle of His.
Cordis, Latin for "of the heart", may refer to:
Cordis Corporation develops and manufacturers diagnostic and interventional products to treat patients who suffer from coronary and peripheral vascular diseases. It was founded in 1959 in Miami, Florida. Cordis Corporation is a company of Cardinal Health. The Cordis global headquarters and a Europe, Middle East and Africa hub are located in Zug, Switzerland. North American operations are based out of the San Francisco Bay area. The Asia-Pacific hub is located in Singapore, and the Latin American hub is located in Puerto Rico.
The Medical Development Corporation was founded in 1957 in Miami, Florida, by Dr. William P. Murphy Jr. and focused on interventional vascular medicine and neuroscience. In 1959 the company’s name changed to Cordis. Cordis joined the Johnson & Johnson interventional business called “Johnson & Johnson Intervention Systems (JJIS)” and forms Cordis Corporation in 1996. In 1997 Cordis Corporation expanded into the rapidly growing field of electrophysiology through the acquisition of Biosense Inc. One year later, in 1998, Biosense Inc. merged with Webster Laboratories to form Biosense Webster, Inc.
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